6 completed, 2 not yet recruiting. 5 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Not yet recruiting 2 |
| Phase 1 | 4 | Completed 4 |
Follow EC-18: new trials by email Literature Review of EC-18 trials Research Report on EC-18
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Determine the Dose-dependent Efficacy and Safety of EC-18 in Patients With Moderate to Severe Atopic Dermatitis EC-18, Placebo EC-18 - Atopic Dermatitis | Phase 2 | Not yet recruiting | Enzychem Lifesciences Corporation | 150 | 2027-05-01 | 2026-08-28 |
| Prevention of COVID-19 Infection to Severe Pneumonia or ARDS EC-18, Placebo - Covid19 Pneumonia | Phase 2 | Not yet recruiting | Enzychem Lifesciences Corporation | 60 | 2026-12-30 | 2026-10-21 |
| To Evaluate Safety and Efficacy of EC-18 in COVID-19 Infection to Pneumonia EC-18, Placebo EC-18 - COVID-19 | Phase 2 | Completed | Enzychem Lifesciences Corporation | 63 | 2020-05-28 | 2022-02-10 |
| EC-18 for Oral Mucositis in Patients With Concomitant Chemoirradiation EC-18, Placebo - Stomatitis | Phase 2 | Completed | Enzychem Lifesciences Corporation | 105 | 2018-07-03 | 2023-07-27 |
| Management of Severe Chemotherapy-induced Neutropenia in Advanced Breast Cancer EC-18 - Febrile Neutropenia | Phase 1 / Phase 2 | Completed | Enzychem Lifesciences Corporation | 28 | 2017-10-30 | 2026-11-04 |
| Evaluation of the Food Effect on the Safety, Tolerability, PK of EC-18 After Oral Administration in Healthy Volunteers high-fat diet, EC-18 - Chemotherapy-Induced Neutropenia | Phase 1 | Completed | Enzychem Lifesciences Corporation | 36 | 2015-08-01 | 2016-03-15 |
| A Safety and PK Study of EC-18 in Healthy Subjects EC-18, Placebo - Chemotherapy-induced Neutropenia | Phase 1 | Completed | Enzychem Lifesciences Corporation | 33 | 2015-07-01 | 2016-01-11 |
| Study to Evaluate the Safety, Tolerability and PK of EC-18 After Oral Administration in Healthy Volunteers EC-18, Placebo - Chemotherapy-Induced Neutropenia | Phase 1 | Completed | Enzychem Lifesciences Corporation | 64 | 2015-03-01 | 2016-01-27 |
Neoplasms (2) · Neutropenia (2) · Breast Neoplasms (1) · COVID-19 (1) · Dermatitis, Atopic (1) · Febrile Neutropenia (1) · Stomatitis (1)
Enzychem Lifesciences Corporation (8)
South Korea (4) · United States (3)
Min-Soo Park, Professor (2) · Dong Moon Shin, MD (1) · Hyewon Jeong (1) · Mahesh Kudrimoti, MD (1) · Sung-Bae Kim, MD, PhD (1) · Treva W Tyson, MD (1)