3 completed. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 3 |
Follow difelikefalin: new trials by email Literature Review of difelikefalin trials Research Report on difelikefalin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT) difelikefalin 2.0 mg, Placebo - Pruritus, Notalgia Paresthetica | Phase 2 | Completed | Cara Therapeutics, Inc. | 126 | 2021-01-11 | 2023-05-22 |
| Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis difelikefalin 0.25 mg, difelikefalin 0.5 mg, difelikefalin 1.0 mg - Pruritus, Atopic Dermatitis | Phase 2 | Completed | Cara Therapeutics, Inc. | 401 | 2019-06-29 | 2022-04-04 |
| A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus CR845 0.25 mg Oral Tablet, CR845 0.5 mg Oral Tablet, CR845 1 mg Oral Tablet - Chronic Kidney Diseases, Pruritus | Phase 2 | Completed | Cara Therapeutics, Inc. | 269 | 2018-07-05 | 2024-01-24 |
Pruritus (3) · Dermatitis, Atopic (1) · Eczema (1) · Kidney Failure, Chronic (1) · Renal Insufficiency, Chronic (1)
United States (3) · Canada (2)
Kristine Nograles (1) · Nilam Shah (1)