5 completed. 5 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Phase 2 | 1 | Completed 1 |
Follow DFMO: new trials by email Literature Review of DFMO trials Research Report on DFMO
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral AMXT 1501 Dicaprate in Combination With DFMO AMXT1501, DFMO - Cancer, Solid Tumor | Phase 1 | Completed | Aminex Therapeutics, Inc. | 56 | 2018-06-12 | 2023-05-25 |
| DFMO in Children With Type 1 Diabetes Difluoromethylornithine, Placebo - Type 1 Diabetes | Phase 1 | Completed | Indiana University | 41 | 2015-04-01 | 2021-09-05 |
| Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma DFMO, Bortezomib - Neuroblastoma Recurrent | Phase 1 / Phase 2 | Completed | Giselle Sholler | 16 | 2014-06-06 | 2024-08-06 |
| N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan DFMO, Celecoxib, Cyclophosphamide - Neuroblastoma | Phase 1 | Completed | New Approaches to Neuroblastoma Therapy Consortium | 30 | 2014-01-16 | 2025-02-17 |
| Safety Study for Refractory or Relapsed Neuroblastoma With DFMO Alone and in Combination With Etoposide DFMO, Etoposide - Neuroblastoma | Phase 1 | Completed | Giselle Sholler | 21 | 2010-02-01 | 2024-08-06 |
Neuroblastoma (2) · Diabetes Mellitus, Type 1 (1) · Neoplasms (1)
Giselle Sholler (2) · Aminex Therapeutics, Inc. (1) · Indiana University (1) · New Approaches to Neuroblastoma Therapy Consortium (1)
United States (5) · Australia (1) · Canada (1)
Giselle Sholler, MD (1) · Jackie Walling, MBChB PhD (1) · Kathleen Neville, MD (1) · Michael Hogarty, MD (1) · Nicole Gallegos, BS, MBA (1)
PMID 26018967, PMID 32715853, PMID 37918404, PMID 40913836
P01CA081403 (1)