6 completed. 6 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 6 |
| Phase 1 | 2 | Completed 2 |
Follow Depsipeptides: new trials by email Literature Review of Depsipeptides trials Research Report on Depsipeptides
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell Lymphoma Laboratory Biomarker Analysis, Romidepsin, Venetoclax - Anaplastic Large Cell Lymphoma, Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Phase 2 | Completed | City of Hope Medical Center | 12 | 2018-09-11 | 2026-10-29 |
| Study of Pembrolizumab (MK-3475) in Combination With Romidepsin Pembrolizumab, Romidepsin - Recurrent Anaplastic Large Cell Lymphoma, Recurrent Angioimmunoblastic T-Cell Lymphoma | Phase 1 / Phase 2 | Completed | M.D. Anderson Cancer Center | 38 | 2017-11-14 | 2026-10-28 |
| A Trial of Romidepsin for Progressive or Relapsed Peripheral T-cell Lymphoma Romidepsin - Peripheral T-cell Lymphoma | Phase 2 | Completed | Celgene | 131 | 2007-06-19 | 2020-02-11 |
| FR901228 in Treating Patients With Recurrent High-Grade Gliomas depsipeptide - Adult Anaplastic Astrocytoma, Adult Anaplastic Oligodendroglioma | Phase 1 / Phase 2 | Completed | National Cancer Institute (NCI) | 50 | 2005-01-01 | 2017-01-02 |
| A Single Agent Phase II Study of Romidepsin (Depsipeptide, FK228) in the Treatment of Cutaneous T-cell Lymphoma (CTCL) romidepsin (depsipeptide, FK228) - Cutaneous T-cell Lymphoma | Phase 2 | Completed | Celgene | 102 | 2005-01-01 | 2019-10-30 |
| A Research Study for Patients With Prostate Cancer Romidepsin - Prostate Cancer, Metastases | Phase 2 | Completed | Celgene | 35 | 2003-05-07 | 2019-11-18 |
Lymphoma, T-Cell (3) · Lymphoma, Large-Cell, Anaplastic (2) · Lymphoma, T-Cell, Cutaneous (2) · Astrocytoma (1) · Brain Neoplasms (1) · Glioblastoma (1) · Gliosarcoma (1) · Immunoblastic Lymphadenopathy (1) · Lymphoma, T-Cell, Peripheral (1) · Mycosis Fungoides (1) · Neoplasm Metastasis (1) · Oligodendroglioma (1) · Prostatic Neoplasms (1)
Celgene (3) · City of Hope Medical Center (1) · M.D. Anderson Cancer Center (1) · National Cancer Institute (NCI) (1)
United States (5) · France (2) · Germany (2) · Poland (2) · United Kingdom (2) · Australia (1) · Czechia (1) · Russia (1) · Spain (1) · Sweden (1) · Ukraine (1)
Howard Fine, MD (1) · Jasmine M Zain (1) · Jean Nichols, Ph.D. (1) · Myron Czuczman, MD (1) · Swaminathan P Iyer, MD (1)
PMID 20697094, PMID 21377994, PMID 22271479, PMID 24456586, PMID 25279222, PMID 25605745, PMID 26965915
P30CA033572 (1), U01CA062399 (1)