15 suspended. 15 Phase 2, 4 Phase 3, 3 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 15 | Suspended 15 |
| Phase 3 | 4 | Suspended 4 |
| Phase 1 | 3 | Suspended 3 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Collection - B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, T Acute Lymphoblastic Leukemia | Phase 2 | Suspended | University of Washington | 30 | 2026-05-08 | 2026-09-29 |
| ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma Vevoctadekin, Bone Marrow Aspiration, Bone Marrow Biopsy - Recurrent Diffuse Large B-Cell Lymphoma, Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Phase 1 / Phase 2 | Suspended | Fred Hutchinson Cancer Center | 33 | 2025-12-27 | 2026-09-11 |
| External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Extramedullary Disease in Multiple Myeloma, Multiple Myeloma | Phase 1 / Phase 2 | Suspended | City of Hope Medical Center | 20 | 2025-08-29 | 2026-10-07 |
| Epcoritamab and Tazemetostat for the Treatment of Relapsed or Refractory Grade I-IIIa Follicular Lymphoma Biospecimen Collection, Bone Marrow Biopsy, Computed Tomography - Recurrent Grade 1 Follicular Lymphoma, Recurrent Grade 2 Follicular Lymphoma | Phase 2 | Suspended | City of Hope Medical Center | 33 | 2025-03-11 | 2026-01-21 |
| Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple Myeloma Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy - Multiple Myeloma | Phase 2 | Suspended | National Cancer Institute (NCI) | 84 | 2024-08-27 | 2026-10-19 |
| Testing the Combination of the Anticancer Drug Durvalumab With Chemotherapy (Gemcitabine and Cisplatin) at Improving Outcomes for High-Risk Resectable Liver Cancer Before Surgery Biopsy Procedure, Biospecimen Collection, Cisplatin - Resectable Intrahepatic Cholangiocarcinoma | Phase 2 | Suspended | National Cancer Institute (NCI) | 27 | 2024-07-10 | 2026-09-04 |
| Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer Biospecimen Collection, Bone Scan, Clinical Observation - Castration-Resistant Prostate Carcinoma, Stage IVB Prostate Cancer AJCC v8 | Phase 2 | Suspended | Mayo Clinic | 236 | 2024-05-03 | 2026-08-20 |
| Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer Biospecimen Collection, Cabozantinib S-malate, Computed Tomography - Metastatic Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Carcinoma | Phase 2 | Suspended | National Cancer Institute (NCI) | 50 | 2024-02-19 | 2026-10-19 |
| Cemiplimab Plus Fianlimab for the Treatment of Locally Advanced Head and Neck Basal Cell Carcinoma Before Surgery Cemiplimab, Computed Tomography, Biospecimen Collection - Locally Advanced Basal Cell Carcinoma, Basal Cell Carcinoma | Phase 2 | Suspended | Thomas Jefferson University | 70 | 2023-07-05 | 2026-06-10 |
| A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma Bone Scan, Cabozantinib S-malate, Cisplatin - High Grade Osteosarcoma, Localized Osteosarcoma | Phase 2 / Phase 3 | Suspended | National Cancer Institute (NCI) | 1122 | 2023-03-03 | 2026-10-27 |
| Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer Biopsy Procedure, Biospecimen Collection, Computed Tomography - Locally Advanced Pancreatic Adenocarcinoma, Stage III Pancreatic Cancer AJCC v8 | Phase 1 / Phase 2 | Suspended | National Cancer Institute (NCI) | 92 | 2021-01-11 | 2026-10-20 |
| Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial Atezolizumab, Biospecimen Collection, Computed Tomography - Extensive Stage Lung Small Cell Carcinoma | Phase 2 / Phase 3 | Suspended | National Cancer Institute (NCI) | 138 | 2021-01-07 | 2026-10-21 |
| Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery Biospecimen Collection, Carboplatin, Computed Tomography - Clinical Stage II Esophageal Adenocarcinoma AJCC v8, Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 | Phase 2 / Phase 3 | Suspended | National Cancer Institute (NCI) | 278 | 2019-05-03 | 2026-10-22 |
| Stereotactic Body Radiation Therapy in Treating Patients With Oligometastatic Renal Cell Carcinoma Biopsy, Biospecimen Collection, Computed Tomography - Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8 | Phase 2 | Suspended | M.D. Anderson Cancer Center | 123 | 2018-06-14 | 2026-10-06 |
| Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer Atezolizumab, Biopsy Procedure, Biospecimen Collection - Oropharyngeal p16INK4a-Negative Squamous Cell Carcinoma, Stage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Phase 2 / Phase 3 | Suspended | National Cancer Institute (NCI) | 613 | 2013-03-22 | 2026-10-14 |
Multiple Myeloma (2) · Adenocarcinoma Of Esophagus (1) · Burkitt Lymphoma (1) · Carcinoma, Basal Cell (1) · Carcinoma, Renal Cell (1) · Lymphoma, Follicular (1) · Lymphoma, Large B-Cell, Diffuse (1) · Nasopharyngeal Carcinoma (1) · Osteosarcoma (1) · Pancreatic Neoplasms (1) · Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (1) · Prostatic Neoplasms (1) · Squamous Cell Carcinoma of Head and Neck (1)
National Cancer Institute (NCI) (8) · City of Hope Medical Center (2) · Fred Hutchinson Cancer Center (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1) · Thomas Jefferson University (1) · University of Washington (1)
United States (15) · Canada (2) · Australia (1) · Hong Kong (1) · New Zealand (1)
Alexandre V. Hirayama, MD (1) · Ari J Rosenberg (1) · Chad Tang (1) · Hop S Tran Cao (1) · Jennifer R Eads (1) · Joseph Curry, MD (1) · Matthew P. Thorpe, M.D., Ph.D. (1) · Michael W Bishop (1) · Paul M Harari (1) · Quynh-Nhu Nguyen (1) · Ryan D. Cassaday, MD (1) · Sarah L Davis (1) · Sascha A Tuchman (1) · Scott R Goldsmith (1) · Swetha Kambhampati (1)
PMID 34717797, PMID 40915303, PMID 41671459
P30CA033572 (2), U10CA180821 (2), U10CA180868 (2), P30CA016672 (1), U10CA021661 (1), U10CA180820 (1), U10CA180886 (1), UM1CA186688 (1), UM1CA186691 (1)