4 completed, 1 terminated, 1 withdrawn. 6 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Terminated 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 2, Terminated 1, Withdrawn 1 |
Follow CR011-vcMMAE: new trials by email Literature Review of CR011-vcMMAE trials Research Report on CR011-vcMMAE
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Glembatumumab Vedotin, Nivolumab, and Ipilimumab in Treating Patients With Advanced Metastatic Solid Tumors That Cannot Be Removed by Surgery Glembatumumab Vedotin, Ipilimumab, Laboratory Biomarker Analysis - Advanced Malignant Solid Neoplasm, Estrogen Receptor Negative | Phase 1 / Phase 2 | Withdrawn | National Cancer Institute (NCI) | 2018-04-20 | 2018-07-18 | |
| Study of Glembatumumab Vedotin in gpNMB-Expressing, Advanced or Metastatic SCC of the Lung Phase I: Glembatumumab Vedotin, Phase II: Glembatumumab Vedotin - Squamous Cell Carcinoma of the Lung | Phase 1 / Phase 2 | Terminated | PrECOG, LLC. | 13 | 2016-04-10 | 2019-07-16 |
| Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma Glembatumumab Vedotin, Laboratory Biomarker Analysis, Pharmacological Study - Recurrent Osteosarcoma | Phase 2 | Completed | National Cancer Institute (NCI) | 22 | 2016-02-16 | 2022-01-18 |
| Glembatumumab Vedotin in Treating Patients With Metastatic or Locally Recurrent Uveal Melanoma Glembatumumab Vedotin, Laboratory Biomarker Analysis, Pharmacological Study - Recurrent Uveal Melanoma, Stage IV Uveal Melanoma AJCC v7 | Phase 2 | Completed | National Cancer Institute (NCI) | 37 | 2015-09-16 | 2020-08-21 |
| Study of CR011-vcMMAE to Treat Locally Advanced or Metastatic Breast Cancer CR011-vcMMAE - Breast Cancer | Phase 1 / Phase 2 | Completed | CuraGen Corporation | 42 | 2008-06-01 | 2015-02-19 |
| A Phase I/II Study of CR011-vcMMAE in Subjects With Unresectable Stage III or Stage IV Melanoma CR011-vcMMAE - Unresectable Stage III or Stage IV Melanoma | Phase 1 / Phase 2 | Completed | CuraGen Corporation | 117 | 2006-06-01 | 2015-02-19 |
Breast Neoplasms (2) · Melanoma (2) · Uveal Melanoma (2) · Neoplasm Metastasis (1) · Osteosarcoma (1) · Triple Negative Breast Neoplasms (1)
National Cancer Institute (NCI) (3) · CuraGen Corporation (2) · PrECOG, LLC. (1)
United States (5) · Canada (1) · Puerto Rico (1)
Haeseong Park (1) · Lisa M Kopp (1) · Rathi Pillai, MD (1) · Sapna Patel (1)
PMID 25267741, PMID 25267761, PMID 31401903, PMID 31586757
N01CM00039 (1), U10CA180886 (1), UM1CA186704 (1), UM1CA186712 (1)