6 completed, 2 no longer available, 2 terminated, 2 unknown. 5 Phase 2, 2 Early Phase 1, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 2, Unknown 2, Terminated 1 |
| Early Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Unknown 1 |
Follow COVID-19 convalescent plasma: new trials by email Literature Review of COVID-19 convalescent plasma trials Research Report on COVID-19 convalescent plasma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessment of Efficacy and Safety of Therapy With COVID-19 Convalescent Plasma in Subjects With Severe COVID-19 (IPCO) COVID-19 convalescent plasma - Severe COVID-19 | Phase 2 | Unknown | University of Erlangen-Nürnberg Medical School | 58 | 2021-01-18 | 2021-01-20 |
| Convalescent Plasma (PC) and Human Intravenous Anti-COVID-19 Immunoglobulin (IV Anti COVID-19 IgG) in Patients Hospitalized for COVID-19. COVID-19 convalescent plasma, Anti-COVID-19 human immunoglobulin, Standard (specific) therapy for COVID-19 - Coronavirus Disease 2019 (COVID-19) | Phase 2 / Phase 3 | Unknown | Lifefactors Zona Franca, SAS | 75 | 2020-09-01 | 2020-07-10 |
| ANTIBODY-LEVEL BASED ANALYSIS OF COVID-19 CONVALESCENT SERUM (ABACCuS) COVID-19 convalescent plasma - COVID-19, Severe Acute Respiratory Syndrome (SARS) | Phase 2 | Terminated | Corewell Health East | 71 | 2020-07-16 | 2022-03-09 |
| Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure Multiple Doses of Anti-SARS-CoV-2 convalescent plasma - Covid-19, Sars-CoV2 | Early Phase 1 | Terminated | Noah Merin | 6 | 2020-06-27 | 2021-11-08 |
| Use of Multiple Doses of Convalescent Plasma in Mechanically Intubated Patients With COVID-19 Multiple doses of anti-SARS-CoV-2 Convalescent Plasma - COVID-19 | Early Phase 1 | Completed | Hospital Regional Dr. Rafael Estévez | 30 | 2020-06-06 | 2022-10-27 |
| Early transfusIon of Convalescent Plasma in Elderly COVID-19 Patients. to Prevent Disease Progression. COVID-19 Convalescent Plasma - Coronavirus Disease 2019 )COVID-19) | Phase 2 / Phase 3 | Completed | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 29 | 2020-05-27 | 2021-05-28 |
| COVID-19 Convalescent Plasma for the Treatment of Hospitalized Patients With Pneumonia Caused by SARS-CoV-2. COVID-19 Convalescent Plasma - COVID-19 | Phase 1 | Completed | University of Pennsylvania | 80 | 2020-05-13 | 2022-04-19 |
| Efficacy and Safety of Early COVID-19 Convalescent Plasma in Patients Admitted for COVID-19 Infection COVID-19 convalescent plasma - Severe Acute Respiratory Syndrome Coronavirus 2 | Phase 2 | Completed | Pontificia Universidad Catolica de Chile | 58 | 2020-05-04 | 2020-09-16 |
| Observational Study of Convalescent Plasma for Treatment of Veterans With COVID-19 COVID-19 convalescent plasma - Coronavirus Disease 2019 (COVID-19) | Completed | VA Office of Research and Development | 5044 | 2020-05-01 | 2024-04-04 | |
| COVID-19 Convalescent Plasma for Mechanically Ventilated Population COVID-19 Convalescent Plasma - Covid-19 | Phase 1 | Completed | University of Pennsylvania | 32 | 2020-04-30 | 2022-04-04 |
| Convalescent Plasma for the Treatment of Patients With COVID-19 COVID-19 Convalescent Plasma - COVID-19, SARS-CoV 2 | No longer available | University of Colorado, Denver | 2020-08-28 | |||
| Expanded Access to Convalescent Plasma for the Treatment of Patients With COVID-19 COVID-19 convalescent plasma - COVID19 | Approved for marketing | Mayo Clinic | 2020-09-02 | |||
| Investigational COVID-19 Convalescent Plasma Infusion for Severely or Life-threateningly Ill COVID-19 Patients COVID-19 Convalescent Plasma - COVID-19, SARS-CoV 2 | No longer available | Rutgers, The State University of New Jersey | 2023-11-28 |
COVID-19 (12) · Coronavirus Infections (4) · Severe Acute Respiratory Syndrome (2) · Critical Illness (1)
University of Pennsylvania (2) · Corewell Health East (1) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (1) · Hospital Regional Dr. Rafael Estévez (1) · Lifefactors Zona Franca, SAS (1) · Mayo Clinic (1) · Noah Merin (1) · Pontificia Universidad Catolica de Chile (1) · Rutgers, The State University of New Jersey (1) · University of Colorado, Denver (1) · University of Erlangen-Nürnberg Medical School (1) · VA Office of Research and Development (1)
United States (8) · Chile (1) · Colombia (1) · Germany (1) · Italy (1) · Panama (1)
Carsten Willam, MD (1) · David Hager, MD PhD (1) · John D Beckham, MD (1) · Katharine J. Bar (1) · Katharine J. Bar, MD (1) · Marc Klapholz, MD, MBA (1) · Maria Elvira Balcells, MD (1) · Matthew Sims, MD PhD (1) · Michael J Gaziano, MD MPH (1) · Michael Joyner, MD (1) · Nicholas L. Smith, PhD (1) · Noah Merin, MD PhD (1) · Ricardo Aguilar, M.D (1)
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