11 completed. 11 Phase 2, 4 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 11 | Completed 11 |
| Phase 1 | 4 | Completed 4 |
Follow Chidamide: new trials by email Literature Review of Chidamide trials Research Report on Chidamide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low-dose Chidamide Maintenance Therapy After Allo-HSCT for T-cell Acute Lymphoblastic Leukemia or T-cell Lymphomas Chidamide - T Lymphoblastic Leukemia/Lymphoma | Phase 2 | Completed | Zhejiang University | 44 | 2023-07-15 | 2025-12-05 |
| A Study of Tucidinostat Combined With Tislelizumab as First-line Treatment in Advanced NSCLC Tucidinostat, Tislelizumab - Non Small Cell Lung Cancer | Phase 2 | Completed | Chipscreen Biosciences, Ltd. | 118 | 2022-10-26 | 2026-04-20 |
| A Proof-of-concept Trial to Evaluate the Safety and Efficacy of UB-421 Plus Chidamide in Changing HIV Reservoirs UB-421, chidamide - HIV-1 Infection | Phase 2 | Completed | United BioPharma | 11 | 2021-12-02 | 2023-02-15 |
| Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC. Chidamide, Envafolimab - Non Small Cell Lung Cancer | Phase 2 | Completed | Chipscreen Biosciences, Ltd. | 34 | 2021-11-23 | 2024-08-07 |
| A Clinical Trial of Chidamide in the Management of Refractory ITP Chidamide - Thrombocytopenia | Phase 1 / Phase 2 | Completed | Shandong University | 61 | 2021-06-01 | 2025-08-26 |
| Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma Chidamide - Bladder Cancer Stage IV | Phase 2 | Completed | Sun Yat-sen University | 45 | 2021-01-01 | 2026-10-30 |
| Neoadjuvant Tucidinostat and Exemestane in Early Breast Cancer Tucidinostat, Exemestane, Ovarian function suppression - Breast Cancer | Phase 2 | Completed | First Affiliated Hospital, Sun Yat-Sen University | 30 | 2020-07-08 | 2023-10-17 |
| Chiauranib in Combination With Chidamide in Patients With Relapsed/Refractory Non-Hodgkin's Lymphoma Chiauranib, Chidamide - Non-hodgkin's Lymphoma | Phase 1 / Phase 2 | Completed | Chipscreen Biosciences, Ltd. | 9 | 2019-07-11 | 2022-03-09 |
| Sintilimab in Combination With Chidamide in Refractory and Relapsed ENKTCL Sintilimab, Chidamide - Safety and Efficacy | Phase 1 / Phase 2 | Completed | Huiqiang Huang | 40 | 2019-03-29 | 2022-04-14 |
| Chidamide in Combination With Antiretroviral Therapy for Eradication of the Latent HIV-1 Reservoir Chidamide - Chronic HIV Infections | Phase 1 / Phase 2 | Completed | Tang-Du Hospital | 13 | 2015-08-01 | 2020-01-18 |
| Chidamide in Combination With Carboplatin and Paclitaxel in Advanced Non-small Cell Lung Cancer Chidamide, Paclitaxel, Carboplatin - Non-small-cell Lung Cancer | Phase 2 | Completed | Chipscreen Biosciences, Ltd. | 124 | 2013-04-01 | 2016-02-01 |
Carcinoma, Non-Small-Cell Lung (3) · Breast Neoplasms (1) · Lymphoma (1) · Lymphoma, Non-Hodgkin (1) · Recurrence (1) · Thrombocytopenia (1) · Urinary Bladder Neoplasms (1)
Chipscreen Biosciences, Ltd. (4) · First Affiliated Hospital, Sun Yat-Sen University (1) · Huiqiang Huang (1) · Shandong University (1) · Sun Yat-sen University (1) · Tang-Du Hospital (1) · United BioPharma (1) · Zhejiang University (1)
China (10) · Taiwan (1)
Caicun Zhou (1) · Jianfang Zhou (1) · Li Zhang (1) · Ying Lin, MD (1) · Yongtao Sun, M.D., Ph.D. (1) · Yuankai Shi (1)