1 completed, 1 terminated, 1 withdrawn. 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
Follow Carbaglu: new trials by email Literature Review of Carbaglu trials Research Report on Carbaglu
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Short-Term Outcome of N-Carbamylglutamate in the Treatment of Acute Hyperammonemia Carbaglu, Placebo - Propionic Acidemia, Type I and/or Type II, Methylmalonic Acidemia | Phase 2 | Completed | Mendel Tuchman | 35 | 2012-09-01 | 2021-02-15 |
| Long-term Outcome of N-Carbamylglutamate Treatment in Propionic Acidemia and Methylmalonic Acidemia N-carbamylglutamate, Standard of Care - Propionic Acidemia, Methylmalonic Acidemia | Phase 2 | Terminated | Mendel Tuchman | 1 | 2012-09-01 | 2017-04-26 |
| Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate N-carbamylglutamate - Urea Cycle Disorders, Inborn, Inborn Errors of Metabolism | Phase 2 | Withdrawn | Children's Hospital of Philadelphia | 2010-12-01 | 2014-05-29 |
Methylmalonic acidemia (3) · Propionic Acidemia (3) · Carbamoyl-Phosphate Synthase I Deficiency Disease (2) · Hyperammonemia (1) · Metabolism, Inborn Errors (1) · Ornithine Carbamoyltransferase Deficiency Disease (1) · Urea Cycle Disorders, Inborn (1)
Mendel Tuchman (2) · Children's Hospital of Philadelphia (1)
United States (2)
Mendel Tuchman, MD (2) · Marc Yudkoff, MD (1)
PMID 18414145, PMID 19660971, PMID 20338795, PMID 20566609, PMID 33006765
R01HD058567 (1)