9 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 3 Phase 1, 3 Phase 2, 2 Early Phase 1, 2 Phase 4, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 2 | 3 | Completed 3 |
| Early Phase 1 | 2 | Active not recruiting 1, Completed 1 |
| Phase 4 | 2 | Completed 2 |
| Not applicable | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Cantharidin: new trials by email Literature Review of Cantharidin trials Research Report on Cantharidin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-Term Follow-up Study of Cantharidin (YCANTH [VP-102/TO-208]) in Patients With Common Warts (Verruca Vulgaris) Cantharidin - Common Warts (Verruca Vulgaris), Common Warts | Phase 3 | Recruiting | Verrica Pharmaceuticals Inc. | 250 | 2026-03-11 | 2026-10-22 |
| Investigation of the Distinct Mechanisms Involved in Inflammatory Resolution Between Healthy Men and Women Cantharidin - Inflammation | Early Phase 1 | Active not recruiting | Queen Mary University of London | 34 | 2022-12-12 | 2026-07-16 |
| Cold Atmospheric Plasma Device for Pediatric Molluscum and Verruca Floating electrode-dielectric barrier device (FE-DBD) cold atmospheric plasma (CAP), Cryotherapy, Canthardin Collodion - Verruca Vulgaris, Molluscum Contagiosum Skin Infection | Phase 4 | Completed | Medical University of South Carolina | 17 | 2021-12-02 | 2024-04-05 |
| A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts VP-102 and applicator, Placebo - Condylomata Acuminata, Papillomavirus Infections | Phase 2 | Completed | Verrica Pharmaceuticals Inc. | 105 | 2019-06-25 | 2024-11-27 |
| First-time-in-Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single (in Both Fed and Fasted States) or Repeat Doses of GSK3358699 Placebo, GSK3358699, GM-CSF - Arthritis, Rheumatoid | Phase 1 | Terminated | GlaxoSmithKline | 48 | 2018-03-13 | 2020-12-02 |
| Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects Cantharidin, Lipopolysaccharide, Granulocyte-Macrophage Colony-Stimulating Factor - Arthritis, Rheumatoid | Phase 1 | Completed | GlaxoSmithKline | 12 | 2017-08-11 | 2019-08-08 |
| Safety and Efficacy of Topical Cantharidin for the Treatment of Molluscum Contagiosum, Phase 2 Cantharidin - Molluscum Contagiosum | Phase 2 | Completed | Steven R Cohen | 30 | 2016-09-01 | 2019-01-30 |
| Safety and Efficacy Study of Topical Cantharidin for the Treatment of Molluscum Contagiosum Cantharidin, Placebo, Gauze occlusion bandage - Molluscum Contagiosum | Phase 2 | Completed | Montefiore Medical Center | 94 | 2012-07-01 | 2017-05-05 |
| Investigation of the Influence of Gender on Cardiovascular Function Typhoid vaccine, Cantharidin - Cardiovascular Function | Early Phase 1 | Completed | Queen Mary University of London | 56 | 2012-03-01 | 2017-06-14 |
| Cantharidin-induced Skin Blister for Testing Anti-inflammatory Effects of Macrolides Cantharidin, Azithromycin, Placebo - Inflammation | Phase 1 | Completed | GlaxoSmithKline | 44 | 2009-06-04 | 2017-07-25 |
| A Trial Examining the Treatment of Common Warts With Combination Liquid Nitrogen (LN2) and Cantharidin Liquid nitrogen and cantharidin, Liquid nitrogen and topical placebo - Verruca Vulgaris | Not applicable | Completed | North Idaho Dermatology | 70 | 2007-06-01 | 2010-03-11 |
| Cantharone for the Treatment of Perenial Warts Cantharidin, Trichloroacetic Acid - Wart, Genital | Phase 4 | Completed | Wayne State University | 12 | 2006-06-15 | 2018-08-10 |
Warts (5) · Inflammation (3) · Arthritis, Rheumatoid (2) · Condylomata Acuminata (2) · Molluscum Contagiosum (2) · Blister (1) · Papillomavirus Infections (1) · Sexually Transmitted Diseases (1) · Sexually Transmitted Diseases, Viral (1) · Skin Diseases (1) · Skin Diseases, Infectious (1) · Skin Diseases, Viral (1) · Virus Diseases (1)
GlaxoSmithKline (3) · Queen Mary University of London (2) · Verrica Pharmaceuticals Inc. (2) · Medical University of South Carolina (1) · Montefiore Medical Center (1) · North Idaho Dermatology (1) · Steven R Cohen (1) · Wayne State University (1)
United Kingdom (5) · United States (5) · Japan (1)
Adelaide A Hebert, MD (1) · Amrita Ahluwalia, BSC PhD (1) · Amrita Ahluwalia, BSc PhD (1) · Lara Wine Lee, MD, PhD (1) · Richard A Flygare, PhD (1) · Scott Guenthner, MD (1) · Steven R Cohen, MD, MPH (1)
PMID 27893465, PMID 13519856, PMID 23629714, PMID 24643186, PMID 26239450, PMID 30031863, PMID 34515985, PMID 34773923, PMID 34849299, PMID 39197495
2017 (1)