5 completed, 1 terminated. 4 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 4 | Completed 3, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
Follow BTRX-335140: new trials by email Literature Review of BTRX-335140 trials Research Report on BTRX-335140
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| To Evaluate the Effects of NMRA-335140 on Symptoms of Major Depression in Participants With Bipolar II Disorder. NMRA-335140 80 mg, Placebo - Major Depressive Episode Associated With Bipolar II Disorder | Phase 2 | Completed | Neumora Therapeutics, Inc. | 18 | 2024-05-13 | 2026-03-30 |
| Study to Assess the Effects of Oral NMRA-335140 in Participants With Major Depressive Disorder NMRA-335140, Placebo - Major Depressive Disorder | Phase 3 | Completed | Neumora Therapeutics, Inc. | 422 | 2023-12-21 | 2026-07-06 |
| Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder NMRA-335140, Placebo - Major Depressive Disorder | Phase 3 | Completed | Neumora Therapeutics, Inc. | 430 | 2023-12-20 | 2026-07-06 |
| Study to Assess the Safety and Effectiveness of NMRA-335140-501 NMRA-335140 - Major Depressive Disorder | Phase 3 | Terminated | Neumora Therapeutics, Inc. | 904 | 2023-11-10 | 2026-09-14 |
| Study to Evaluate the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder NMRA-335140, Placebo - Major Depressive Disorder | Phase 3 | Completed | Neumora Therapeutics, Inc. | 383 | 2023-09-20 | 2025-11-26 |
| Study in Major Depressive Disorder With NMRA-335140 (BTRX-335140) vs Placebo NMRA-335140, Placebo - Major Depressive Disorder | Phase 2 | Completed | Neumora Therapeutics, Inc. | 204 | 2020-01-03 | 2025-05-29 |
Depressive Disorder, Major (5) · Bipolar Disorder (1)
Neumora Therapeutics, Inc. (6)
United States (6) · Brazil (2) · Bulgaria (2) · Canada (2) · Chile (2) · Czechia (2) · Finland (2) · France (2) · Germany (2) · Poland (2) · Sweden (2)