18 completed. 18 Phase 1.
By phase and status
Follow BI 425809: new trials by email Literature Review of BI 425809 trials Research Report on BI 425809
Trials (filtered) newest first · largest first
All 18 trials
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems
Iclepertin - Hepatic Insufficiency | Phase 1 | Completed | 29 | 2023-03-08 | 2026-04-24 |
A Study in Healthy Men to Test Whether Bosentan Influences the Amount of BI 425809 in the Blood
BI 425809, Bosentan - Healthy | Phase 1 | Completed | 14 | 2023-03-06 | 2026-03-30 |
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Kidney Problems
BI 425809 - Renal Insufficiency | Phase 1 | Completed | 36 | 2023-02-01 | 2026-03-30 |
A Study in Healthy Women to Test Whether BI 425809 Influences the Amount of a Contraceptive in the Blood
Microgynon®, Iclepertin - Healthy | Phase 1 | Completed | 19 | 2022-11-24 | 2026-05-06 |
A Study in Healthy People to Test How BI 425809 is Taken up in the Body When Taken With or Without Food
BI 425809 - Healthy | Phase 1 | Completed | 16 | 2022-10-25 | 2026-04-20 |
A Study in Healthy Men to Test Whether BI 425809 Influences the Amount of Midazolam in the Blood
midazolam, iclepertin (BI 425809) - Healthy | Phase 1 | Completed | 15 | 2022-03-18 | 2026-03-30 |
A Study in Healthy Men to Test How Fluconazole Influences the Amount of BI 425809 in the Blood
BI 425809, fluconazole - Healthy | Phase 1 | Completed | 15 | 2021-10-19 | 2026-05-04 |
A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine
Lamotrigine, BI 409306, Placebo - Healthy | Phase 1 | Completed | 40 | 2020-12-01 | 2024-03-12 |
A Study in Healthy Men and Women to Test Which Effects Memantine and BI 425809 Have on Each Other
BI 425809, Memantine - Healthy | Phase 1 | Completed | 16 | 2019-07-17 | 2021-04-13 |
A Study in Healthy Men and Women to Test Which Effects Donepezil and BI 425809 Have on Each Other
BI 425809, Donepezil - Healthy | Phase 1 | Completed | 32 | 2019-04-12 | 2021-02-17 |
A Study in Healthy Men to Measure the Amount of BI 425809 in the Blood When Taken as a Tablet
BI 425809, [C-14]-BI 425809 - Healthy | Phase 1 | Completed | 6 | 2019-01-15 | 2026-03-27 |
A Study in Healthy Men to Test Whether Rifampicin Influences the Amount of BI 425809 in the Blood
Rifampicin, BI 425809 - Healthy | Phase 1 | Completed | 16 | 2017-03-28 | 2026-03-30 |
Interaction of BI 425809 With Midazolam, Warfarin, Omeprazole and Digoxin
Midazolam, Warfarin, Omeprazole - Healthy | Phase 1 | Completed | 13 | 2015-09-07 | 2026-04-15 |
Single Rising Dose Trial of BI 425809 for Healthy Japanese and Chinese Male Subjects
BI 425809, Placebo - Healthy | Phase 1 | Completed | 49 | 2015-05-11 | 2026-03-30 |
Pharmacokinetics and Pharmacodynamic Effect of Different Multiple Oral Doses of BI 425809
BI 425809 - Healthy | Phase 1 | Completed | 25 | 2015-02-23 | 2026-05-01 |
Relative Bioavailability of a Single Oral Dose of BI 425809 When Administered Alone or in Combination With Multiple Oral Doses of Itraconazole in Healthy Male Subjects
BI 425809, Itraconazole - Healthy | Phase 1 | Completed | 16 | 2015-01-29 | 2026-10-02 |
Safety, Tolerability, and Pharmacokinetics of Multiple Rising Doses of BI 425809 Tablets for 12 Days to Young and Elderly Healthy Male and Female Volunteers and Comparison of Pharmacokinetics of a Single Oral Dose of BI 425809 (Morning Versus Evening)
BI 425809, Placebo - Healthy | Phase 1 | Completed | 96 | 2015-01-15 | 2026-05-13 |
Safety, Tolerability, and Pharmacokinetics of Single Doses BI 425809
BI 425809 PfOS, Placebo PfOS, BI 425809 tablet - Healthy | Phase 1 | Completed | 83 | 2014-03-20 | 2026-06-03 |
Conditions studied
Hepatic Insufficiency (1) · Renal Insufficiency (1)
Sponsors
Boehringer Ingelheim (18)
Countries
Germany (14) · Belgium (1) · Netherlands (1) · South Korea (1) · United States (1)
Results publications
PMID 34716565, PMID 41903096, PMID 29076028, PMID 29846887, PMID 31005336, PMID 34936055, PMID 36700734, PMID 40676451, PMID 40906309
NIH funding
2014 (3), 2018 (2), 2015 (1), 2016 (1), 2019 (1)