6 completed, 1 terminated, 1 unknown. 5 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 5 | Completed 4, Unknown 1 |
Follow BCT-100: new trials by email Literature Review of BCT-100 trials Research Report on BCT-100
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Evaluating the Safety and Activity of Pegylated Recombinant Human Arginase (BCT-100) PEG- BCT-100 - Cancer, Pediatric Solid Tumor | Phase 1 / Phase 2 | Completed | University of Birmingham | 49 | 2018-08-28 | 2022-09-02 |
| Efficacy and Safety Study of Recombinant Human Arginase 1 in Patients With Relapsed or Refractory Acute Myeloid Leukemia PEG-BCT-100 - Acute Myeloid Leukemia | Phase 2 | Unknown | Bio-Cancer Treatment International Limited | 25 | 2016-09-01 | 2017-07-28 |
| Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors PEG-BCT-100 - Melanoma, Prostate Adenocarcinoma | Phase 1 | Completed | Bio-Cancer Treatment International Limited | 23 | 2014-11-01 | 2020-04-24 |
| Pegylated Recombinant Human Arginase 1 in Combination With Oxaliplatin and Capecitabine for the Treatment of HCC PACOX - Hepatocellular Carcinoma | Phase 2 | Completed | Bio-Cancer Treatment International Limited | 17 | 2014-04-01 | 2017-07-28 |
| Efficacy Study of Pegylated Recombinant Human Arginase 1 as a Second-line Therapy in Patients With Advanced Liver Cancer pegylated recombinant human arginase - Hepatocellular Carcinoma | Phase 2 | Completed | Bio-Cancer Treatment International Limited | 27 | 2014-04-01 | 2021-08-09 |
| A Pilot Study of Recombinant Human Arginase 1 (rhArg1) in Patients With Relapsed or Refractory Leukemia or Lymphoma Recombinant human arginase 1 Peg5000 - Leukemia, Lymphoma | Phase 1 | Terminated | Bio-Cancer Treatment International Limited | 1 | 2012-04-01 | 2017-07-31 |
| Study of Pegylated Human Recombinant Arginase for Liver Cancer (BCT-100-002) Pegylated Recombinant Human Arginase I - Neoplasm, Hepatocellular Carcinoma | Phase 1 / Phase 2 | Completed | Bio-Cancer Treatment International Limited | 20 | 2010-03-01 | 2012-03-14 |
| Study of Pegylated Human Recombinant Arginase for Liver Cancer Pegylated Recombinant Human Arginase I, Doxorubicin - Neoplasm, Hepatocellular Carcinoma | Phase 1 | Completed | Bio-Cancer Treatment International Limited | 15 | 2008-05-01 | 2012-03-14 |
Carcinoma, Hepatocellular (4) · Neoplasms (3) · Leukemia (1) · Leukemia, Myeloid, Acute (1) · Lymphoma (1) · Melanoma (1) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (1)
Bio-Cancer Treatment International Limited (7) · University of Birmingham (1)
Hong Kong (5) · Australia (1) · China (1) · Netherlands (1) · United Kingdom (1) · United States (1)
Ronnie TP Poon, Prof (2) · Alan K Chiang, Dr. (1) · Alberto Bessudo, MD (1) · Anskar Leung (1) · Francis J Mussai, DPhil (1) · Stephen L Chan, Dr. (1) · Steven O'Day, MD (1) · Thomas CC Yau, Dr. (1)