2 completed, 1 recruiting, 1 terminated. 2 Phase 2, 2 Phase 3.
By phase and status
Follow ATM-AVI: new trials by email Literature Review of ATM-AVI trials Research Report on ATM-AVI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|
Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections
ATM-AVI, BAT - Gram-negative Bacterial Infections | Phase 2 | Recruiting | 48 | 2023-04-18 | 2026-10-29 |
Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria
ATM-AVI, BAT - Serious Bacterial Infection | Phase 3 | Terminated | 15 | 2020-12-25 | 2024-02-02 |
A Study to Determine the Efficacy, Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI) ± Metronidazole (MTZ) Versus Meropenem (MER) ± Colistin (COL) for the Treatment of Serious Infections Due to Gram Negative Bacteria.
ATM-AVI, MTZ, MER - Complicated Intra-abdominal Infection, Hosptial Acquired Pneumonia | Phase 3 | Completed | 422 | 2018-04-05 | 2024-12-10 |
Determine the PK and Safety and Tolerability of ATM-AVI for the Treatment of cIAIs in Hospitalized Adults (REJUVENATE)
ATM-AVI, Metronidazole - Complicated Intra-Abdominal Infections, cIAIs | Phase 2 | Completed | 40 | 2016-05-19 | 2020-04-02 |
Conditions studied
Gram-Negative Bacterial Infections (1) · Pneumonia, Ventilator-Associated (1)
Sponsors
Pfizer (4)
Countries
China (3) · Greece (3) · India (3) · Spain (3) · Taiwan (3) · United States (3) · Argentina (2) · Malaysia (2) · Mexico (2) · Philippines (2) · Romania (2) · Russia (2) · Thailand (2) · Turkey (Türkiye) (2) · Bulgaria (1)
Top investigators
Oliver Cornely (1)
Results publications
PMID 38252170, PMID 40530972, PMID 41269522, PMID 31828337, PMID 35115349, PMID 39389071
NIH funding
2017 (2), 2015 (1)