4 terminated, 3 completed, 2 active not recruiting, 2 withdrawn. 9 Phase 2, 3 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 9 | Completed 3, Terminated 3, Active not recruiting 1, Recruiting 1, Withdrawn 1 |
| Phase 3 | 3 | Active not recruiting 1, Terminated 1, Withdrawn 1 |
| Phase 1 | 1 | Terminated 1 |
Follow Atacicept: new trials by email Literature Review of Atacicept trials Research Report on Atacicept
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Atacicept in Multiple Glomerular Diseases Atacicept - pMN, IgAN | Phase 2 | Recruiting | Vera Therapeutics, Inc. | 250 | 2025-07-07 | 2026-06-26 |
| Monthly Dosing of Atacicept in IgAN Atacicept - IgA Nephropathy (IgAN), Berger Disease | Phase 2 | Active not recruiting | Vera Therapeutics, Inc. | 90 | 2025-05-29 | 2026-04-13 |
| Atacicept in Subjects With IgA Nephropathy Atacicept, Placebo to match Atacicept - IgA Nephropathy, Berger Disease | Phase 3 | Active not recruiting | Vera Therapeutics, Inc. | 428 | 2023-06-29 | 2026-10-01 |
| Atacicept in Subjects With Active Lupus Nephritis (COMPASS) Atacicept, Placebo - Lupus Nephritis (LN) | Phase 3 | Withdrawn | Vera Therapeutics, Inc. | 2022-11-02 | 2025-05-23 | |
| Atacicept Demonstrating Dose RESponSe Placebo, Atacicept - Systemic Lupus Erythematosus | Phase 2 | Withdrawn | EMD Serono | 2012-02-01 | 2013-08-21 | |
| Atacicept in Lupus Nephritis Patients Taking Stable Regimen of Mycophenolate Mofetil Atacicept - Lupus Nephritis | Phase 1 | Terminated | EMD Serono | 1 | 2011-06-01 | 2013-10-22 |
| Atacicept in Subjects With Optic Neuritis Atacicept, Placebo matched to atacicept - Optic Neuritis | Phase 2 | Terminated | EMD Serono | 34 | 2008-06-01 | 2016-02-17 |
| A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS) Atacicept, Placebo matched to atacicept - Relapsing Multiple Sclerosis | Phase 2 | Terminated | EMD Serono | 255 | 2008-04-01 | 2016-05-24 |
| Atacicept in Combination With Rituximab in Subjects With Rheumatoid Arthritis (August III) Rituximab, Atacicept, Placebo matched to atacicept - Rheumatoid Arthritis | Phase 2 | Completed | Merck KGaA, Darmstadt, Germany | 27 | 2008-03-01 | 2016-12-30 |
| The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis Atacicept, Mycophenolate mofetil, Placebo - Lupus Nephritis | Phase 2 / Phase 3 | Terminated | EMD Serono | 6 | 2007-12-01 | 2016-03-23 |
| Atacicept in Anti-Tumor Necrosis Factor Alpha-naïve Subjects With Rheumatoid Arthritis (AUGUST II) Placebo matched to atacicept, Atacicept: with loading dose, Atacicept - Rheumatoid Arthritis | Phase 2 | Completed | EMD Serono | 311 | 2007-09-01 | 2016-02-17 |
| A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I) Atacicept, Placebo matched to atacicept - Rheumatoid Arthritis | Phase 2 | Completed | EMD Serono | 256 | 2006-12-01 | 2016-02-17 |
Arthritis, Rheumatoid (3) · Glomerulonephritis, IGA (3) · Lupus Nephritis (3) · Lupus Erythematosus, Systemic (2) · Nephritis (2) · Arthritis (1) · Autoimmune Diseases (1) · Glomerulonephritis (1) · Immune System Diseases (1) · Kidney Diseases (1) · Macular dystrophy, corneal type 1 (1) · Nephrotic Syndrome (1) · Neuritis (1) · Optic Neuritis (1)
EMD Serono (7) · Vera Therapeutics, Inc. (4) · Merck KGaA, Darmstadt, Germany (1)
United States (10) · Canada (3) · Czechia (3) · France (3) · Germany (3) · Spain (3) · United Kingdom (3) · Australia (2) · Belgium (2) · Lebanon (2) · Netherlands (2) · Sweden (2) · Switzerland (2) · Austria (1) · Lithuania (1)
Eric Michael, MD (1) · Joanne Curley (1) · Pam Winterberg (1) · Stephen Wax, MD, PhD (1) · Zeeshan Khawaja (1)
PMID 21452293, PMID 21452294, PMID 22325903, PMID 24613349, PMID 26137975, PMID 39462308, PMID 41196369, PMID 41620980