astegolimab: Clinical Trials

5 trials of astegolimab, newest first

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5 completed. 5 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 25Completed 5

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Trials (filtered) newest first · largest first

All 5 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Study to Evaluate the Efficacy and Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Astegolimab, Placebo - Chronic Obstructive Pulmonary Disease
Phase 2CompletedGenentech, Inc.13342021-10-052026-10-16
A Study to Evaluate the Safety and Efficacy of MSTT1041A (Astegolimab) or UTTR1147A in Patients With Severe COVID-19 Pneumonia
MSTT1041A, MSTT1041A-matched Placebo, UTTR1147A - COVID-19 Pneumonia
Phase 2CompletedGenentech, Inc.3962020-06-022022-01-10
A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Moderate to Severe Atopic Dermatitis
MSTT1041A, Placebo - Atopic Dermatitis
Phase 2CompletedGenentech, Inc.652019-02-062023-05-06
Anti-ST2 (MSTT1041A) in COPD (COPD-ST2OP)
MSTT1041A, Placebo - COPD Exacerbation
Phase 2CompletedUniversity of Leicester812018-10-112022-06-21
A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma
MSTT1041A, Placebo - Asthma
Phase 2CompletedHoffmann-La Roche5172016-09-202022-12-28

Conditions studied

Pulmonary Disease, Chronic Obstructive (2)  ·  Asthma (1)  ·  Dermatitis, Atopic (1)

Sponsors

Genentech, Inc. (3)  ·  Hoffmann-La Roche (1)  ·  University of Leicester (1)

Countries

United States (4)  ·  Germany (3)  ·  Poland (3)  ·  Argentina (2)  ·  Belgium (2)  ·  Bulgaria (2)  ·  Canada (2)  ·  Czechia (2)  ·  Mexico (2)  ·  New Zealand (2)  ·  Peru (2)  ·  Romania (2)  ·  South Africa (2)  ·  South Korea (2)  ·  Spain (2)

Top investigators

Christopher Brightling, Prof (1)

Results publications

PMID 33872652, PMID 35339234, PMID 36253275, PMID 36519984, PMID 42148875, PMID 42150581

NIH funding

2018 (2), 2016 (1)