4 recruiting, 1 active not recruiting. 2 Phase 1, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 2 |
| Phase 2 | 1 | Recruiting 1 |
Follow ASP3082: new trials by email Literature Review of ASP3082 trials Research Report on ASP3082
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Compare Setidegrasib (ASP3082) With Docetaxel, in People With Non-small Cell Lung Cancer With a KRAS G12D Mutation Setidegrasib, Docetaxel - Non-small Cell Lung Cancer (NSCLC) | Phase 3 | Recruiting | Astellas Pharma Global Development, Inc. | 356 | 2026-04-28 | 2026-10-20 |
| Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance ASP3082 - Metastatic/Locally Advanced Non-Small-Cell Lung Cancer, Metastatic/Locally Pancreatic Ductal Adenocarcinoma | Phase 2 | Recruiting | Gustave Roussy, Cancer Campus, Grand Paris | 60 | 2026-03-25 | 2026-08-05 |
| A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer Setidegrasib, Oxaliplatin, Leucovorin - Pancreatic Cancer, Metastatic Pancreatic Cancer | Phase 3 | Recruiting | Astellas Pharma Global Development, Inc. | 614 | 2026-02-17 | 2026-09-22 |
| A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults Setidegrasib, Fluconazole, Carbamazepine - Healthy Volunteer | Phase 1 | Active not recruiting | Astellas Pharma Global Development, Inc. | 54 | 2026-02-03 | 2026-08-27 |
| A Study of ASP3082 in Adults With Advanced Solid Tumors Setidegrasib, Cetuximab, Leucovorin - Solid Tumor | Phase 1 | Recruiting | Astellas Pharma Inc | 681 | 2022-06-08 | 2026-10-14 |
Neoplasm Metastasis (2) · Carcinoma, Non-Small-Cell Lung (1) · Neoplasms (1) · Pancreatic Neoplasms (1)
Astellas Pharma Global Development, Inc. (3) · Astellas Pharma Inc (1) · Gustave Roussy, Cancer Campus, Grand Paris (1)
United States (4) · China (3) · Japan (3) · France (2) · South Korea (2) · Puerto Rico (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
2025 (1)