4 terminated, 2 completed. 4 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 2, Terminated 2 |
| Phase 2 | 2 | Terminated 2 |
Follow APD791: new trials by email Literature Review of APD791 trials Research Report on APD791
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Assess the Effect of Oral Temanogrel on Digital Blood Flow in Adult Participants With Raynaud's Phenomenon Secondary to Systemic Sclerosis Temanogrel, Placebo - Raynaud's Phenomenon Secondary to Systemic Sclerosis | Phase 2 | Terminated | Pfizer | 13 | 2021-11-03 | 2023-12-22 |
| A Study Evaluating the Safety, Tolerability, and Effect on Microvascular Obstruction of Intravenous Temanogrel in Adult Participants Undergoing Percutaneous Coronary Intervention Temanogrel, Placebo - Microvascular Obstruction | Phase 2 | Terminated | Pfizer | 29 | 2021-05-20 | 2023-12-12 |
| Dose-escalation, Repeated and Single Oral Dosing Study APD791, Clopidogrel, Aspirin - Acute Coronary Syndrome | Phase 1 | Terminated | IlDong Pharmaceutical Co Ltd | 104 | 2015-03-01 | 2019-02-15 |
| Safety Study of APD-791 With Aspirin and/or Clopidogrel Clopidogrel, Aspirin, APD791 - Acute Coronary Syndrome | Phase 1 | Terminated | IlDong Pharmaceutical Co Ltd | 16 | 2014-02-01 | 2019-02-15 |
| A Multiple-Dose Study to Assess the Safety, Tolerability, and Steady State Pharmacokinetics of APD791 in Healthy Volunteers APD791 - Healthy | Phase 1 | Completed | Arena Pharmaceuticals | 50 | 2008-01-01 | 2022-07-05 |
| Single-Dose Safety Study of APD791 in Healthy Volunteers APD791 - Healthy | Phase 1 | Completed | Arena Pharmaceuticals | 90 | 2007-07-01 | 2008-12-30 |
Acute Coronary Syndrome (2) · Raynaud Disease (1) · Scleroderma, Systemic (1)
Arena Pharmaceuticals (2) · IlDong Pharmaceutical Co Ltd (2) · Pfizer (2)
United States (4) · United Kingdom (2) · Australia (1) · Netherlands (1) · Sweden (1)
Christen Anderson, MD, PhD (1) · Christen M Anderson, MD, PhD (1) · Gyunseop Bae, M.D. (1) · James Kisicki, MD (1)