3 completed, 1 terminated, 1 unknown. 2 Phase 1, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 2 | Completed 1, Terminated 1 |
| Phase 2 | 2 | Completed 2 |
| Phase 4 | 1 | Unknown 1 |
Follow Antithrombins: new trials by email Literature Review of Antithrombins trials Research Report on Antithrombins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19 Antithrombin + best available treatment, Best available treatment - Covid19, Severe Acute Respiratory Syndrome | Phase 2 | Completed | Maimónides Biomedical Research Institute of Córdoba | 48 | 2020-04-27 | 2021-02-09 |
| Bivalirudin in Late PCI for Oatients With STEMI Bivalirudin, Heparin - STEMI - ST Elevation Myocardial Infarction | Phase 4 | Unknown | Second Xiangya Hospital of Central South University | 1200 | 2019-11-30 | 2019-12-10 |
| Safety and Efficacy of Preoperative Antithrombin Supplementation in Patients Undergoing High-Risk Cardiopulmonary Bypass AT-III (Human), Placebo - Cardiac Surgery, Cardiopulmonary Bypass | Phase 2 | Completed | Grifols Therapeutics LLC | 425 | 2014-06-26 | 2019-03-15 |
| Understanding "Heparin Resistance" in Cardiac Surgery Heparin, ATryn - Cardiopulmonary Bypass, Altered Heparin Response | Phase 1 | Completed | Massachusetts General Hospital | 504 | 2012-06-01 | 2016-12-14 |
| Antithrombin III Supplementation for Cardiopulmonary Bypass in Neonates Antithrombin (Recombinant), Placebo - Postoperative Hemorrhage | Phase 1 | Terminated | Medical College of Wisconsin | 8 | 2011-08-01 | 2014-01-20 |
COVID-19 (1) · Postoperative Hemorrhage (1) · Pulmonary Atelectasis (1) · ST Elevation Myocardial Infarction (1) · Severe Acute Respiratory Syndrome (1)
Grifols Therapeutics LLC (1) · Maimónides Biomedical Research Institute of Córdoba (1) · Massachusetts General Hospital (1) · Medical College of Wisconsin (1) · Second Xiangya Hospital of Central South University (1)
United States (3) · Spain (1)
Greg Koski, MD, PhD (1) · Robert A Niebler, M.D. (1)