4 active not recruiting, 3 recruiting. 7 Phase 3.
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Follow amivantamab: new trials by email Literature Review of amivantamab trials Research Report on amivantamab
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Trial Phase Status Sponsor Enrollment Start Updated
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer Amivantamab, Pembrolizumab, Carboplatin - Squamous Cell Carcinoma of Head and Neck Phase 3 Recruiting 500 2025-12-03 2026-09-25
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy Amivantamab, Cetuximab, Bevacizumab - Colorectal Neoplasms Phase 3 Recruiting 700 2024-12-12 2026-09-25
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer Amivantamab, Cetuximab, 5-fluorouracil - Colorectal Neoplasms Phase 3 Recruiting 1000 2024-10-18 2026-09-25
A Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung Cancer Lazertinib, Amivantamab Subcutaneous and Co-Formulated with Recombinant Human Hyaluronidase (SC CF), Amivantamab Intravenous - Advanced or Metastatic Non-small Cell Lung Cancer Phase 3 Active not recruiting 418 2022-08-05 2026-09-28
A Study of Amivantamab and Lazertinib in Combination With Platinum-Based Chemotherapy Compared With Platinum-Based Chemotherapy in Patients With Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non- Small Cell Lung Cancer After Osimertinib Failure Lazertinib, Amivantamab, Pemetrexed - Carcinoma, Non-Small-Cell Lung Phase 3 Active not recruiting 776 2021-11-17 2026-09-28
A Study of Combination Amivantamab and Carboplatin-Pemetrexed Therapy, Compared With Carboplatin-Pemetrexed, in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Characterized by Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions Amivantamab, Pemetrexed, Carboplatin - Carcinoma, Non-Small-Cell Lung Phase 3 Active not recruiting 308 2020-10-13 2026-10-29
A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer Amivantamab, Osimertinib, Lazertinib - Carcinoma, Non-Small-Cell Lung Phase 3 Active not recruiting 1074 2020-09-30 2026-09-28
Conditions studied Carcinoma, Non-Small-Cell Lung (4) · Colorectal Neoplasms (2) · Squamous Cell Carcinoma of Head and Neck (1)
Sponsors Janssen Research & Development, LLC (7)
Countries Brazil (7) · China (7) · France (7) · Germany (7) · Italy (7) · Japan (7) · Poland (7) · South Korea (7) · Spain (7) · Taiwan (7) · United Kingdom (7) · United States (7) · Belgium (6) · India (6) · Israel (6)
Results publications PMID 34911336 , PMID 37870976 , PMID 38857463 , PMID 38924756 , PMID 40617394 , PMID 40922529 , PMID 40923797 , PMID 41184595 , PMID 41671628 , PMID 42192224 , PMID 42635093 , PMID 42870814
NIH funding 2023 (3) , 2025 (1)