20 completed, 1 withdrawn. 8 Phase 1, 7 Phase 3, 6 Phase 2.
By phase and status
Follow aleglitazar: new trials by email Literature Review of aleglitazar trials Research Report on aleglitazar
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix .
Trial Phase Status Sponsor Enrollment Start Updated
A Study of Alegitazar in Patients With Type 2 Diabetes And Chronic Kidney Disease (Alerenal Study) Aleglitazar, Placebo - Diabetes Mellitus Type 2, Kidney Disease, Chronic Phase 3 Withdrawn 2013-12-01 2016-11-02 A Study of Aleglitazar in Monotherapy in Patients With Type 2 Diabetes Mellitus Who Are Drug-Naïve to Anti-Hyperglycemic Therapy aleglitazar, placebo - Diabetes Mellitus Type 2 Phase 3 Completed 13 2013-06-01 2016-11-02 A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin Monotherapy aleglitazar, metformin, placebo - Diabetes Mellitus Type 2 Phase 3 Completed 7 2013-05-01 2016-11-02 A Study of Aleglitazar in Combination With Metformin in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Sulfonylurea Alone or Sulfonylurea Plus Metformin Therapy aleglitazar, placebo - Diabetes Mellitus Type 2 Phase 3 Completed 197 2012-12-01 2016-11-02 A Study of The Effect of Aleglitazar on Insulin Sensitivity in Patients With Type 2 Diabetes Mellitus Who Are Inadequately Controlled With Metformin aleglitazar, metformin, placebo - Diabetes Mellitus Type 2 Phase 2 Completed 57 2012-12-01 2016-11-02 A Study on The Potential of Aleglitazar to Reduce Cardiovascular Risk in Patients With Stable Cardiovascular Disease and Glucose Abnormalities Placebo, aleglitazar - Cardiovascular Disease, Diabetes Mellitus Type 2 Phase 3 Completed 1999 2012-12-01 2016-11-02 A Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus Who Have Not Previously Received Anti-Hyperglycemic Therapy Placebo, aleglitazar - Diabetes Mellitus Type 2 Phase 3 Completed 196 2012-11-01 2016-08-11 A Pharmacokinetic Study of Aleglitazar in Healthy Chinese Volunteers aleglitazar - Healthy Volunteer Phase 1 Completed 16 2012-11-01 2016-11-02 A Study to Evaluate the Effect of Aleglitazar on Cardiac Energetics and Function in Patients With Type 2 Diabetes Mellitus and no History of Coronary Artery Disease aleglitazar, placebo - Diabetes Mellitus Type 2 Phase 2 Completed 18 2012-10-01 2016-11-02 A Pharmacokinetics Study of Aleglitazar in Combination With Digoxin in Healthy Volunteers aleglitazar, digoxin - Healthy Volunteer Phase 1 Completed 28 2012-10-01 2016-11-02 A Study to Investigate the Effects of Rifampicin on the Pharmacokinetics of Aleglitazar in Healthy Volunteers aleglitazar, rifampicin - Healthy Volunteer Phase 1 Completed 24 2012-08-01 2016-11-02 A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers Aleglitazar, Microgynon®, Placebo - Healthy Volunteer Phase 1 Completed 18 2012-07-01 2016-11-02 A Pharmacodynamic/Pharmacokinetic Study of Aleglitazar in Patients With Type 2 Diabetes Mellitus on Treatment With Lisinopril aleglitazar, lisinopril, placebo - Diabetes Mellitus Type 2 Phase 1 Completed 55 2011-08-01 2016-11-02 A Study of The Effect of Hepatic Impairment on The Pharmacokinetics of Aleglitazar aleglitazar - Healthy Volunteer Phase 1 Completed 38 2010-09-01 2015-12-24 A Study of Aleglitazar in Combination With Aspirin in Healthy Volunteers aleglitazar, aspirin, placebo - Healthy Volunteer Phase 1 Completed 44 2010-07-01 2016-11-02 A Study of Aleglitazar in Combination With Ibuprofen in Healthy Volunteers aleglitazar, placebo, ibuprofen - Healthy Volunteer Phase 1 Completed 44 2010-06-01 2012-05-22 A Study of Aleglitazar in Type 2 Diabetes Patients With Moderate Renal Impairment aleglitazar, pioglitazone - Diabetes Mellitus Type 2 Phase 2 Completed 302 2010-05-01 2016-11-02 A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus Aleglitazar, Placebo - Diabetes Mellitus Type 2 Phase 3 Completed 7226 2010-02-01 2016-11-02 A Comparison of the Effects of Aleglitazar and Actos on Renal Function on Patients With Type 2 Diabetes. Actos, aleglitazar - Diabetes Mellitus Type 2 Phase 2 Completed 176 2007-06-01 2016-08-01 A Comparative Study of Aleglitazar and Actos in Patients With Type 2 Diabetes Mellitus and New York Heart Association (NYHA) Class II Heart Failure. Actos, aleglitazar - Diabetes Mellitus Type 2 Phase 2 Completed 14 2007-05-01 2016-08-05
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Conditions studied Diabetes Mellitus, Type 2 (14) · Bronchiolitis Obliterans Syndrome (1) · Cardiovascular Diseases (1) · Kidney Diseases (1)
Sponsors Hoffmann-La Roche (21)
Countries United States (11) · Mexico (8) · Russia (6) · United Kingdom (6) · Romania (5) · China (4) · Germany (4) · Italy (4) · Argentina (3) · Australia (3) · Colombia (3) · Hong Kong (3) · Hungary (3) · Malaysia (3) · South Korea (3)
Results publications PMID 25728612 , PMID 19515415 , PMID 24016490 , PMID 24682069 , PMID 25407798 , PMID 29903845
NIH funding 2009 (2)