4 completed, 3 unknown, 1 terminated, 1 withdrawn. 6 Phase 1, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Completed 4, Terminated 1, Withdrawn 1 |
| Phase 2 | 3 | Unknown 3 |
Follow AIDSVAX B-E: new trials by email Literature Review of AIDSVAX B-E trials Research Report on AIDSVAX B-E
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Effect of Late Boost on HIV-uninfected Vaccines From EV06 Trial DNA-HIV-PT123 & AIDSVAX B/E - HIV/AIDS | Phase 1 | Completed | EuroVacc Foundation | 49 | 2017-03-15 | 2019-02-07 |
| Study to Evaluate the Safety and Immunogenicity of an Oral HIV Vaccine in Healthy, HIV-uninfected Adults Ad4-mgag, Ad4-EnvC150, Placebo Comparator - Healthy Volunteer, HIV Vaccine | Phase 1 | Terminated | Emergent BioSolutions | 20 | 2015-03-01 | 2024-03-18 |
| Safety and Immunogenicity Study of a DNA Vaccine Combined With Protein Vaccine Against HIV/AIDS DNA, AIDSVAX B/E - HIV/AIDS | Phase 1 | Completed | EuroVacc Foundation | 72 | 2014-09-01 | 2016-01-22 |
| Study of Immune Responses Induced by a HIV Vaccine AIDSVAX B/E, AIDSVAX B/E Placebo - HIV Infections | Phase 2 | Unknown | U.S. Army Medical Research and Development Command | 40 | 2014-07-03 | 2019-09-19 |
| Evaluating the Safety and Immune Response to Different Combinations of the DNA-HIV-PT123 and AIDSVAX® B/E Vaccines in Healthy, HIV-Uninfected Adults AIDSVAX B/E Vaccine, DNA-HIV-PT123 Vaccine, Placebo for DNA-HIV-PT123 - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 104 | 2014-07-01 | 2021-10-15 |
| Study of Boosting Strategies After Vaccination With ALVAC-HIV and AIDSVAX® B/E ALVAC-HIV, AIDSVAX B/E, ALVAC-HIV Placebo - HIV Infections | Phase 2 | Unknown | U.S. Army Medical Research and Development Command | 360 | 2013-09-24 | 2021-03-26 |
| Safety of and Immune Response to Vaccination With 2 Experimental HIV Vaccines in Healthy Adults ALVAC-HIV, AIDSVAX B/E, Placebo for ALVAC-HIV - HIV Infection | Phase 1 | Completed | HIV Vaccine Trials Network | 202 | 2013-06-18 | 2019-06-21 |
| Study of Late Boost Strategies for HIV-uninfected Participants From Protocol RV 144 ALVAC-HIV, AIDSVAX B/E, ALVAC-HIV Placebo - HIV Infections | Phase 2 | Unknown | U.S. Army Medical Research and Development Command | 162 | 2012-04-01 | 2020-11-03 |
| Evaluating the Safety and Immune Response to Five Different Combinations of HIV Vaccines in Healthy, HIV-Uninfected Adults DNA-HIV-PT123, NYVAC-HIV-PT1, NYVAC-HIV-PT4 - HIV Infections | Phase 1 | Withdrawn | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-10-15 |
HIV Infections (6) · Acquired Immunodeficiency Syndrome (2) · Trematode Infections (1)
U.S. Army Medical Research and Development Command (3) · EuroVacc Foundation (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · Emergent BioSolutions (1) · HIV Vaccine Trials Network (1)
Thailand (3) · Uganda (2) · United States (2) · South Africa (1)
Michael Keefer (2) · Pontiano Kaleebu (2) · Glenda Gray, MD (1) · Jintanat Ananworanich, MD, PhD (1) · Nittaya Phanuphak,, MD, PhD (1) · Punnee Pitisuttithum, MD, DTM&H (1) · Sean Bennett, MD (1) · Supachai Rerks-Ngarm, MD (1)
PMID 40190112, PMID 25401780, PMID 28235027, PMID 28329190, PMID 31566579, PMID 31999736, PMID 32035516, PMID 32577626, PMID 34843602, PMID 36762930, PMID 37256916, PMID 37260254