2 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 4 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Unknown 1 |
| Phase 2 | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Terminated 1 |
Follow AGuIX: new trials by email Literature Review of AGuIX trials Research Report on AGuIX
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma Polysiloxane Gd-Chelates based nanoparticles (AGuIX), radiotherapy, Temozolomide - Glioblastoma | Phase 1 / Phase 2 | Active not recruiting | Centre Jean Perrin | 66 | 2022-03-07 | 2026-10-22 |
| Nano-SMART: Nanoparticles With MR Guided SBRT in Centrally Located Lung Tumors and Pancreatic Cancer AGuIX, Radiotherapy - Non-small Cell Lung Cancer, Advanced Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | Recruiting | Dana-Farber Cancer Institute | 100 | 2021-05-27 | 2026-05-14 |
| Evaluating AGuIX® Nanoparticles in Combination With Stereotactic Radiation for Brain Metastases AGuIX - Brain Metastases | Phase 2 | Terminated | Centre Leon Berard | 1 | 2020-01-17 | 2021-06-08 |
| Radiotherapy of Multiple Brain Metastases Using AGuIX® AGuIX®, Whole Brain Radiation Therapy - Brain Metastases, Adult, Radiotherapy | Phase 2 | Completed | University Hospital, Grenoble | 106 | 2019-03-26 | 2026-09-15 |
| AGuIX Gadolinium-based Nanoparticles in Combination With Chemoradiation and Brachytherapy Polysiloxane Gd-Chelates based nanoparticles (AGuIX), External beam radiotherapy (EBRT), Uterovaginal brachytherapy - Gynecologic Cancer | Phase 1 | Unknown | Gustave Roussy, Cancer Campus, Grand Paris | 18 | 2018-05-17 | 2021-07-07 |
| Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles AGuIX, whole brain radiation therapy - Brain Metastases | Phase 1 | Completed | University Hospital, Grenoble | 15 | 2016-03-01 | 2019-06-07 |
Brain Neoplasms (3) · Carcinoma, Non-Small-Cell Lung (1) · Glioblastoma (1)
University Hospital, Grenoble (2) · Centre Jean Perrin (1) · Centre Leon Berard (1) · Dana-Farber Cancer Institute (1) · Gustave Roussy, Cancer Campus, Grand Paris (1)
France (5) · United States (1)
Jonathan Leeman, MD (1) · Juliette Moreau, Md (1)
PMID 30755445, PMID 37060055, PMID 37084803, PMID 40847743
2015 (1), 2016 (1)