5 terminated, 2 completed. 6 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 6 | Terminated 4, Completed 2 |
| Phase 2 | 4 | Terminated 4 |
Follow AEG 35156: new trials by email Literature Review of AEG 35156 trials Research Report on AEG 35156
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AEG35156 in Combination With High-dose Cytarabine and Idarubicin in AML Following Failure of a Single Standard Dose Cytarabine Based Frontline Induction Regimen AEG35156 - Leukemia | Phase 2 | Terminated | Aegera Therapeutics | 60 | 2009-11-01 | 2011-07-13 |
| A Phase 1-2, XIAP Antisense AEG35156 With Weekly Paclitaxel in Patients With Advanced Breast Cancer AEG35156 - Human Mammary Carcinoma | Phase 1 / Phase 2 | Terminated | Aegera Therapeutics | 61 | 2007-11-01 | 2009-12-02 |
| A Phase 1-2 XIAP Antisense AEG35156 With Carboplatin and Paclitaxel in Patients With Advanced Non-Small Cell Lung Cancer AEG35156 - Carcinoma, Non-Small-Cell Lung | Phase 1 / Phase 2 | Terminated | Aegera Therapeutics | 54 | 2007-09-01 | 2009-07-30 |
| A Phase 1-2, XIAP Antisense AEG35156 With Gemcitabine in Patients With Advanced Pancreatic Cancer AEG35156 - Carcinoma, Pancreas | Phase 1 / Phase 2 | Terminated | Aegera Therapeutics | 48 | 2007-09-01 | 2009-12-01 |
| AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors AEG35156, docetaxel, protein expression analysis - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | NCIC Clinical Trials Group | 27 | 2006-07-27 | 2023-08-04 |
| Study of XIAP Antisense for Advanced Cancers AEG35156 - Advanced Cancer | Phase 1 | Terminated | Aegera Therapeutics | 30 | 2006-06-01 | 2008-08-21 |
| AEG35156 and Docetaxel in Treating Patients With Solid Tumors AEG35156, docetaxel - Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | Completed | NCIC Clinical Trials Group | 10 | 2005-06-09 | 2023-08-04 |
Breast Neoplasms (1) · Carcinoma (1) · Carcinoma, Non-Small-Cell Lung (1) · Leukemia (1) · Leukemia, Promyelocytic, Acute (1) · Neoplasms (1)
Aegera Therapeutics (5) · NCIC Clinical Trials Group (2)
United States (4) · Canada (3) · Germany (1) · United Kingdom (1)
Jacques Jolivet, MD, FACP (3) · Gerald Batist, MD (2) · Aaron Schimmer, MD (1) · Daniel D Von Hoff, MD, FACP (1) · David M Loesch, MD (1) · Jacques Jolivet, MD (1) · Robert M Jotte, MD (1)
2009 (1)