4 completed, 2 terminated. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Terminated 2 |
| Phase 1 | 2 | Completed 2 |
Follow ABI-H0731: new trials by email Literature Review of ABI-H0731 trials Research Report on ABI-H0731
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infection ABI-H0731, ETV, Peg-IFNα - Chronic Hepatitis B | Phase 2 | Terminated | Assembly Biosciences | 54 | 2021-02-18 | 2023-10-06 |
| A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitors ABI-H0731, Placebo, NrtI - Chronic Hepatitis B | Phase 2 | Terminated | Assembly Biosciences | 2 | 2020-11-11 | 2022-10-20 |
| A Study Evaluating ABI-H0731+ Entecavir vs Entecavir Alone for the Treatment of Viremic HBeAg-positive Participants With Chronic Hepatitis B Virus Infection (cHBV) ABI-H0731, SOC ETV, Placebo Oral Tablet - Chronic Hepatitis B | Phase 2 | Completed | Assembly Biosciences | 25 | 2018-06-19 | 2021-01-28 |
| A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection ABI-H0731, SOC NUC, Placebo Oral Tablet - Chronic Hepatitis B | Phase 2 | Completed | Assembly Biosciences | 73 | 2018-06-11 | 2021-02-17 |
| Phase 1b/2a Study of ABI-H0731 in Patients With Chronic Hepatitis B ABI-H0731, Placebo for ABI-H0731, Entecavir - Chronic Hepatitis B | Phase 1 / Phase 2 | Completed | Assembly Biosciences | 38 | 2017-06-15 | 2018-07-06 |
| A Study in Healthy Volunteers and Patients With Chronic Hepatitis B ABI-H0731, Placebo for ABI-H0731, Entecavir - Chronic Hepatitis B | Phase 1 | Completed | Assembly Biosciences | 86 | 2016-11-01 | 2019-04-04 |
Hepatitis B, Chronic (6) · Hepatitis B (2)
New Zealand (4) · Hong Kong (3) · United States (3) · Canada (2) · United Kingdom (2) · Australia (1) · China (1) · South Korea (1) · Taiwan (1)
Grace Wang, MD (1) · Steven Knox (1)