10 completed. 10 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 10 |
Follow AA4500: new trials by email Literature Review of AA4500 trials Research Report on AA4500
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Open-label Study to Assess the Safety and Effectiveness of AA4500 in Combination With the ErecAid® Esteem® Manual Vacuum Therapy System in Treating Men With Peyronie's Disease AA4500, ErecAid® Esteem® Manual Vacuum Therapy System, Investigator Modeling - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 30 | 2014-10-01 | 2017-11-08 |
| A Phase 3, Open-label Study of the Safety and Effectiveness of AA4500 Administered Twice Per Treatment Cycle for up to Four Treatment Cycles (2 x 4) in Men With Peyronie's Disease AA4500 - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 189 | 2012-09-01 | 2017-10-05 |
| A Study of AA4500 in Men With Peyronie's Disease AA4500 - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 348 | 2010-11-01 | 2017-10-05 |
| Study of AA4500 in the Treatment of Peyronie's Disease AA4500, Placebo - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 418 | 2010-10-01 | 2017-10-05 |
| Study of AA4500 in the Treatment of Peyronie's Disease AA4500, Placebo - Peyronie's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 418 | 2010-09-01 | 2017-10-05 |
| AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease AA4500 - Advanced Dupuytren's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 286 | 2007-12-01 | 2017-12-02 |
| Safety and Efficacy Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease collagenase clostridium histolyticum - Advanced Dupuytren's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 201 | 2007-10-01 | 2017-12-02 |
| Non-US Study of AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Advanced Dupuytren's Disease collagenase clostridium histolyticum - Advanced Dupuytren's Disease | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 66 | 2007-08-01 | 2017-12-02 |
| AA4500 (XIAFLEX™, Proposed Name) in the Treatment of Dupuytren's Contracture collagenase clostridium histolyticum, Placebo - Dupuytren's Contracture | Phase 3 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 308 | 2007-08-01 | 2017-12-02 |
| Collagenase in the Treatment of Dupuytrens Disease collagenase clostridium histolyticum - Dupuytren's Disease | Phase 3 | Completed | Stony Brook University | 38 | 2003-06-01 | 2010-12-09 |
Penile Induration (5) · Dupuytren Contracture (2)
Endo USA Inc., a Keenova Therapeutics Company (9) · Stony Brook University (1)
United States (7) · Australia (3) · United Kingdom (2) · Denmark (1) · France (1) · Germany (1) · Italy (1) · New Zealand (1) · Spain (1) · Sweden (1)
Veronica Urdaneta, MD (4) · Gregory J. Kaufman, MD (2) · Gregory Kaufman, MD (2) · Lawrence C Hurst, MD (1) · Neil Shusterman, MD (1)
PMID 26199168, PMID 19726771, PMID 21967070, PMID 25388099, PMID 28974406