1 recruiting, 1 terminated. 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Recruiting 1 |
| Phase 3 | 1 | Terminated 1 |
Follow Unresectable HER2-Positive Breast Carcinoma: new trials by email Literature Review of Unresectable HER2-Positive Breast Carcinoma trials Research Report on Unresectable HER2-Positive Breast Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer Biopsy Procedure, Biospecimen Collection, Echocardiography Test - Anatomic Stage III Breast Cancer AJCC v8, Anatomic Stage IV Breast Cancer AJCC v8 | Phase 1 | Recruiting | National Cancer Institute (NCI) | 36 | 2026-10-06 | 2026-10-16 |
| Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer Atezolizumab, Biopsy, Bone Scan - Metastatic Breast Adenocarcinoma, Metastatic HER2-Positive Breast Carcinoma | Phase 3 | Terminated | National Cancer Institute (NCI) | 190 | 2019-04-05 | 2026-05-29 |
Breast Neoplasms (2) · Neoplasm Metastasis (1) · Triple Negative Breast Neoplasms (1)
Breast Diseases (2) · Neoplasms (2) · Neoplasms by Site (2) · Skin Diseases (2) · Skin and Connective Tissue Diseases (2) · Neoplastic Processes (1) · Pathologic Processes (1) · Pathological Conditions, Signs and Symptoms (1)
Biopsy (2) · 2C4 antibody (1) · CT-P6 (1) · CX 5461 (1) · Docetaxel (1) · Magnetic Resonance Spectroscopy (1) · Ogivri (1) · Ontruzant (1) · PF-05280014 (1) · Paclitaxel (1) · Specimen Handling (1) · Taxes (1) · Trastuzumab (1) · atezolizumab (1) · pertuzumab (1)
National Cancer Institute (NCI) (2)
United States (2) · Canada (1)
Charles E Geyer (1) · Filipa Lynce (1)
U10CA180868 (1), UM1CA186709 (1)