3 recruiting. 3 Phase 1, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Recruiting 3 |
| Phase 2 | 2 | Recruiting 2 |
Follow Propionic Acidemia: new trials by email Literature Review of Propionic Acidemia trials Research Report on Propionic Acidemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AAVrh10-PCCA Gene Therapy for Propionic Acidemia AAVrh10-PCCA low dose, AAVrh10-PCCA middle dose, AAVrh10-PCCA high dose - Propionic Acidemia | Phase 1 | Recruiting | Mayo Clinic | 9 | 2026-07-20 | 2026-08-21 |
| A Study to Assess the Long-term Safety and Clinical Activity of mRNA-3927 in Participants Previously Enrolled in the mRNA-3927-P101 Study mRNA-3927 - Propionic Acidemia | Phase 1 / Phase 2 | Recruiting | ModernaTX, Inc. | 50 | 2021-11-09 | 2026-03-23 |
| Open-Label Study of mRNA-3927 in Participants With Propionic Acidemia mRNA-3927 - Propionic Acidemia | Phase 1 / Phase 2 | Recruiting | ModernaTX, Inc. | 77 | 2021-04-15 | 2026-01-22 |
Acid-Base Imbalance (2) · Acidosis (2) · Amino Acid Metabolism, Inborn Errors (2) · Genetic Diseases, Inborn (2) · Metabolic Diseases (2) · Metabolism, Inborn Errors (2)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Nutritional and Metabolic Diseases (3) · Amino Acid Metabolism, Inborn Errors (1) · Genetic Diseases, Inborn (1) · Metabolic Diseases (1) · Metabolism, Inborn Errors (1)
ModernaTX, Inc. (2) · Mayo Clinic (1)
United States (3) · Canada (2) · France (2) · Japan (2) · Netherlands (2) · Saudi Arabia (2) · Spain (2) · United Kingdom (2)