5 completed, 1 recruiting, 1 unknown. 7 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 5, Recruiting 1, Unknown 1 |
Follow Lassa Fever: new trials by email Literature Review of Lassa Fever trials Research Report on Lassa Fever
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Trial to Evaluate the Safety, Immunogenicity and the Optimal Dose of MOPEVAC-Las Vaccine Candidate Against Lassa Fever Low dose MOPEVAC-Las vaccine, Intermediate dose MOPEVAC-Las vaccine, High dose MOPEVAC-Las vaccine - Lassa Fever | Phase 1 | Recruiting | Institut Pasteur | 72 | 2026-09-28 | 2026-10-13 |
| DMID 23-0015; Lassa Fever CVD 1000 LASSARAB+ aPHAD-SEat 700rU, HDCV Comparator, Normal Saline Placebo - Lassa Fever | Phase 1 | Completed | Wilbur Chen, MD, MS | 54 | 2025-01-13 | 2026-09-24 |
| A Clinical Trial to Evaluate the Safety and Immunogenicity of rVSV∆G-LASV-GPC Vaccine in Adults in Good General Heath rVSV∆G-LASV-GPC, Placebo/Diluent - Lassa Fever, Lassa Virus Infection | Phase 1 | Unknown | International AIDS Vaccine Initiative | 114 | 2021-06-23 | 2024-01-18 |
| Dose-ranging Study: Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers in Ghana INO-4500, CELLECTRA™ 2000, Placebo - Lassa Fever | Phase 1 | Completed | Inovio Pharmaceuticals | 220 | 2021-01-27 | 2022-11-21 |
| A Trial to Evaluate the Optimal Dose of MV-LASV (V182-001) MV-LASV, Placebo - Lassa Virus Infection | Phase 1 | Completed | Themis Bioscience GmbH | 60 | 2019-09-26 | 2025-07-11 |
| Multiple Ascending Oral Dose 14-Day Trial of LHF-535 in Healthy Participants LHF-535 - Healthy | Phase 1 | Completed | Kineta Inc. | 24 | 2019-09-16 | 2020-07-09 |
| Safety, Tolerability and Immunogenicity of INO-4500 in Healthy Volunteers INO-4500, Placebo, CELLECTRA® 2000 - Lassa Fever | Phase 1 | Completed | Inovio Pharmaceuticals | 60 | 2019-05-09 | 2020-11-23 |
Arenaviridae Infections (7) · Infections (7) · RNA Virus Infections (7) · Virus Diseases (7) · Hemorrhagic Fevers, Viral (6)
Injections (1) · Rabies Vaccines (1) · Saline Solution (1)
Inovio Pharmaceuticals (2) · Institut Pasteur (1) · International AIDS Vaccine Initiative (1) · Kineta Inc. (1) · Themis Bioscience GmbH (1) · Wilbur Chen, MD, MS (1)
United States (3) · Australia (1) · Belgium (1) · France (1) · Ghana (1) · Liberia (1)
Bonaventure Orizu, MD (1) · Mammen Mammen, MD, FACP, FIDSA (1) · Sylvain Baize (1)
PMID 36934733, PMID 41191941, PMID 41208990, PMID 42265408
2018 (1)