3 active not recruiting, 2 completed, 1 recruiting, 1 terminated. 5 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Active not recruiting 2, Completed 1, Recruiting 1, Terminated 1 |
| Phase 1 | 2 | Active not recruiting 2 |
Follow Kidney Medullary Carcinoma: new trials by email Literature Review of Kidney Medullary Carcinoma trials Research Report on Kidney Medullary Carcinoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors Atezolizumab, Biospecimen Collection, Computed Tomography - Atypical Teratoid/Rhabdoid Tumor, Epithelioid Sarcoma | Phase 1 / Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 86 | 2022-11-17 | 2026-07-14 |
| Testing the Addition of a New Anti-cancer Drug, Radium-223 Dichloride, to the Usual Treatment (Cabozantinib) for Advanced Renal Cell Cancer That Has Spread to the Bone, RadiCaL Study Biospecimen Collection, Bone Scan, Cabozantinib S-malate - Advanced Renal Cell Carcinoma, Chromophobe Renal Cell Carcinoma | Phase 2 | Active not recruiting | National Cancer Institute (NCI) | 98 | 2020-07-29 | 2026-09-28 |
| Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors Biospecimen Collection, Bone Scan, Cabozantinib S-malate - Bladder Adenocarcinoma, Bladder Clear Cell Adenocarcinoma | Phase 2 | Recruiting | National Cancer Institute (NCI) | 314 | 2019-05-13 | 2026-10-26 |
| Phase II Trial of Nivolumab Plus Ipilimumab in Patients With Renal Medullary Carcinoma Ipilimumab, Nivolumab - Kidney Medullary Carcinoma, Loss of INI 1 Protein Expression | Phase 2 | Terminated | M.D. Anderson Cancer Center | 10 | 2018-05-29 | 2026-10-20 |
| Cabozantinib S-malate and Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Genitourinary Tumors Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate - Bladder Small Cell Neuroendocrine Carcinoma, Bladder Squamous Cell Carcinoma | Phase 1 | Active not recruiting | National Cancer Institute (NCI) | 152 | 2015-07-22 | 2026-10-15 |
| Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Pazopanib Hydrochloride - Carcinoma of the Collecting Ducts of Bellini, Chromophobe Renal Cell Carcinoma | Phase 2 | Completed | Mayo Clinic | 38 | 2013-05-16 | 2025-03-03 |
| Study of Kidney Tumors in Younger Patients Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis - Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor | Completed | Children's Oncology Group | 8000 | 2006-02-27 | 2026-05-18 |
Carcinoma, Renal Cell (6) · Oncocytoma, renal (2) · Penile Neoplasms (2) · Urethral Neoplasms (2) · Urinary Bladder Neoplasms (2) · Urogenital Neoplasms (2) · Angiolipoma (1) · Carcinoma, Transitional Cell (1) · Chordoma (1) · Kidney Neoplasms (1) · Nephroma, Mesoblastic (1) · Prostatic Neoplasms (1) · Rhabdoid Tumor (1) · Sarcoma (1) · Urachal adenocarcinoma (1)
Neoplasms (7) · Neoplasms by Histologic Type (7) · Adenocarcinoma (6) · Carcinoma (6) · Female Urogenital Diseases (6) · Female Urogenital Diseases and Pregnancy Complications (6) · Kidney Diseases (6) · Male Urogenital Diseases (6) · Neoplasms by Site (6) · Neoplasms, Glandular and Epithelial (6) · Urogenital Diseases (6) · Urologic Diseases (6) · Urologic Neoplasms (6) · Kidney Neoplasms (5) · Urogenital Neoplasms (4)
Magnetic Resonance Spectroscopy (4) · Specimen Handling (4) · CTLA-4 Antigen (3) · Ipilimumab (3) · Nivolumab (3) · cabozantinib (3) · Biopsy (1) · Fluorodeoxyglucose F18 (1) · Phantoms, Imaging (1) · Tiragolumab (1) · X-Rays (1) · atezolizumab (1) · pazopanib (1) · radium Ra 223 dichloride (1)
National Cancer Institute (NCI) (4) · Children's Oncology Group (1) · M.D. Anderson Cancer Center (1) · Mayo Clinic (1)
United States (7) · Australia (2) · Canada (2) · Puerto Rico (2) · Israel (1) · New Zealand (1) · Switzerland (1)
Andrea B Apolo (2) · Brian Costello, M.D. (1) · Elizabeth A Mullen (1) · Mary F Wedekind Malone (1) · Nizar M Tannir (1) · Rana R McKay (1)
PMID 35031545, PMID 32267967, PMID 32915679, PMID 33604999, PMID 37933882, PMID 38396300, PMID 38954785, PMID 42507969, PMID 42657661
U10CA180821 (2), P30CA016672 (1), U10CA098543 (1), U10CA180886 (1), UG1CA189958 (1), UM1CA186712 (1), UM1CA186716 (1), UM1CA186717 (1), UM1CA228823 (1), ZIABC011078 (1)