2 completed, 1 terminated. 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 1 | Completed 1 |
Follow Hereditary Coproporphyria (HCP): new trials by email Literature Review of Hereditary Coproporphyria (HCP) trials Research Report on Hereditary Coproporphyria (HCP)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP Acute Hepatic Porphyria, Hepatic Porphyrias | Terminated | Alnylam Pharmaceuticals | 212 | 2018-05-29 | 2019-01-25 | |
| ENVISION: A Study to Evaluate the Efficacy and Safety of Givosiran (ALN-AS1) in Patients With Acute Hepatic Porphyrias (AHP) Givosiran, Placebo - Acute Hepatic Porphyria, Acute Intermittent Porphyria | Phase 3 | Completed | Alnylam Pharmaceuticals | 94 | 2017-11-16 | 2024-04-22 |
| Clinical Diagnosis of Acute Porphyria Hereditary Coproporphyria (HCP), Acute Intermittent Porphyria (AIP) | Completed | University of California, San Francisco | 148 | 2011-12-01 | 2021-09-28 |
Coproporphyria, Hereditary (3) · Porphyria, Acute Intermittent (3) · Porphyria, Variegate (3) · Porphyrias (1) · Porphyrias, Hepatic (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Digestive System Diseases (3) · Genetic Diseases, Inborn (3) · Liver Diseases (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Skin Diseases (3) · Skin Diseases, Genetic (3) · Skin and Connective Tissue Diseases (3) · Porphyrias (2) · Porphyrias, Hepatic (2)
givosiran (1)
Alnylam Pharmaceuticals (2) · University of California, San Francisco (1)
United States (3) · Australia (1) · Bulgaria (1) · Canada (1) · Denmark (1) · Finland (1) · France (1) · Germany (1) · Italy (1) · Japan (1) · Mexico (1) · Netherlands (1) · Poland (1) · South Korea (1) · Spain (1)
Bruce Wang, M.D. (1) · Herbert L. Bonkovsky, M.D. (1) · James P. Kushner, M.D. (1) · Joseph R. Bloomer, M.D. (1) · Karl E. Anderson, M.D. (1) · Quinn Dinh, MD (1) · Robert J. Desnick, Ph.D., M.D. (1)
PMID 32521132, PMID 36028858, PMID 37479139, PMID 38044204, PMID 41388232
U54DK083909 (1)