7 completed, 1 withdrawn. 3 Phase 1, 3 Phase 2, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Completed 3 |
| Phase 2 | 3 | Completed 3 |
| Not applicable | 2 | Completed 1, Withdrawn 1 |
Follow AIDS-related Diffuse Large Cell Lymphoma: new trials by email Literature Review of AIDS-related Diffuse Large Cell Lymphoma trials Research Report on AIDS-related Diffuse Large Cell Lymphoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intravenous Chemotherapy or Oral Chemotherapy in Treating Patients With Previously Untreated Stage III-IV HIV-Associated Non-Hodgkin Lymphoma cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma | Phase 2 | Completed | AIDS Malignancy Consortium | 7 | 2016-09-15 | 2022-10-10 |
| Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma carmustine, cytarabine, melphalan - Adult Nasal Type Extranodal NK/T-cell Lymphoma, AIDS-related Diffuse Large Cell Lymphoma | Not applicable | Withdrawn | Fred Hutchinson Cancer Center | 2015-02-01 | 2015-05-07 | |
| RO4929097 and Capecitabine in Treating Patients With Refractory Solid Tumors gamma-secretase/Notch signalling pathway inhibitor RO4929097, capecitabine, laboratory biomarker analysis - Adult Grade III Lymphomatoid Granulomatosis, Adult Nasal Type Extranodal NK/T-cell Lymphoma | Phase 1 | Completed | National Cancer Institute (NCI) | 30 | 2010-06-01 | 2014-11-07 |
| Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy sunitinib malate, pharmacological study, laboratory biomarker analysis - Accelerated Phase Chronic Myelogenous Leukemia, Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Phase 1 | Completed | National Cancer Institute (NCI) | 42 | 2009-08-01 | 2014-03-17 |
| Combination Chemotherapy and Rituximab in Treating Patients With HIV-Associated Stage I, Stage II, Stage III, or Stage IV Non-Hodgkin's Lymphoma rituximab, etoposide, doxorubicin hydrochloride - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Immunoblastic Large Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 106 | 2003-03-01 | 2014-05-14 |
| Bryostatin 1 Plus Vincristine in Treating Patients With Recurrent or Refractory HIV-Related Lymphoma bryostatin 1, vincristine sulfate - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma | Phase 1 | Completed | National Cancer Institute (NCI) | 12 | 2001-11-01 | 2013-01-25 |
| Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment topotecan hydrochloride, laboratory biomarker analysis - AIDS-related Diffuse Large Cell Lymphoma, AIDS-related Diffuse Mixed Cell Lymphoma | Phase 2 | Completed | National Cancer Institute (NCI) | 77 | 2000-04-01 | 2013-02-21 |
| Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenolate Mofetil in Treating HIV-Positive Patients With or Without Cancer fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation - Accelerated Phase Chronic Myelogenous Leukemia, Acute Undifferentiated Leukemia | Not applicable | Completed | Fred Hutchinson Cancer Center | 5 | 1999-11-01 | 2017-05-24 |
Burkitt Lymphoma (5) · Lymphoma, Large B-Cell, Diffuse (5) · Precursor Cell Lymphoblastic Leukemia-Lymphoma (5) · Hodgkin Disease (4) · Immunoblastic Lymphadenopathy (4) · Intraocular Lymphoma (4) · Leukemia, Lymphocytic, Chronic, B-Cell (4) · Lymphoma, B-Cell, Marginal Zone (4) · Lymphoma, Extranodal NK-T-Cell (4) · Lymphoma, Follicular (4) · Lymphoma, Large-Cell, Anaplastic (4) · Lymphoma, Large-Cell, Immunoblastic (4) · Lymphoma, Mantle-Cell (4) · Lymphoma, Non-Hodgkin (4) · Lymphoma, T-Cell, Cutaneous (4)
Hemic and Lymphatic Diseases (6) · Immune System Diseases (6) · Immunoproliferative Disorders (6) · Lymphatic Diseases (6) · Lymphoma, B-Cell (6) · Lymphoproliferative Disorders (6) · Neoplasms (6) · Neoplasms by Histologic Type (6) · DNA Virus Infections (5) · Disease Attributes (5) · Epstein-Barr Virus Infections (5) · Hematologic Diseases (5) · Herpesviridae Infections (5) · Infections (5) · Leukemia, Lymphoid (5)
Etoposide (3) · Vincristine (3) · Cyclophosphamide (2) · Doxorubicin (2) · Peripheral Blood Stem Cell Transplantation (2) · Prednisone (2) · 2,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide (1) · Bryostatins (1) · Capecitabine (1) · Carmustine (1) · Cyclosporine (1) · Cytarabine (1) · Lomustine (1) · Melphalan (1) · Mycophenolic Acid (1)
National Cancer Institute (NCI) (5) · Fred Hutchinson Cancer Center (2) · AIDS Malignancy Consortium (1)
United States (7) · Canada (1) · Kenya (1) · Zimbabwe (1)
Ann Woolfrey (2) · John Deeken (1) · Joseph Sparano (1) · Noelle LoConte (1) · Robert Strother (1) · Scot Remick (1) · Susan Blaney (1)
PMID 18698002, PMID 20023215, PMID 22259028, PMID 24474568, PMID 32107337
P30CA015704 (2), U01CA070019 (2), U01CA121947 (2), P01CA018029 (1), P30CA014520 (1), U01CA062491 (1), U01CA132123 (1), U10CA098543 (1)