59 trials newly registered in Symptoms and General Pathology, first posted 2026-10-21, by therapeutic area, largest first. All areas.
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of HS-10382 Versus Investigator-selected TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP HS-10382, Imatinib, Dasatinib - Chronic Myeloid Leukemia | Phase 3 | Not yet recruiting | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 408 | 2026-12-01 | 2026-10-21 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| A Study of the Safety and Efficacy of Prime Editing (PM647a) in Participants With Alpha-1 Antitrypsin Deficiency PM647a - Alpha-1 Antitrypsin Deficiency, Alpha-1 Antitrypsin Deficiency-associated Lung Disease | Phase 1 / Phase 2 | Not yet recruiting | Prime Medicine, Inc. | 54 | 2026-10-01 | 2026-10-21 |
| Oral Care Program for Mouth Side Effects During Head and Neck Radiation Therapy ORAL CARE PRODUCT KIT - Head and Neck Cancer (H&N), Oral Mucositis (Ulcerative) Due to Radiation | Not applicable | Not yet recruiting | UNCANCER LLC | 50 | 2026-11-01 | 2026-10-21 |
| Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic Immersive Virtual Reality - Pain Management, Injection Pain Prevention | Not applicable | Not yet recruiting | Atlanta VA Medical Center | 45 | 2026-10-01 | 2026-10-21 |
| Chinese Overweight/Obesity Cohort: Metabolic & Comorbidity Risks No intervention; observational assessment only - Obesity & Overweight, Diabetes Mellitus, Type 2 | Not yet recruiting | Shanxi Bethune Hospital | 25974 | 2026-11-01 | 2026-10-21 | |
| A Fifth Proof-of-Concept Study to Evaluate the Efficacy of NOBO, a Novel Postbiotic, in Controlling Axillary Odor in Healthy Adults NOBO postbiotic, Placebo - Body Odor | Not applicable | Active not recruiting | Kingdom | 16 | 2026-10-11 | 2026-10-21 |
| A Study to Learn About the Study Medicine Abrocitinib in People With Severe Atopic Dermatitis Who Have Switched From Other Therapies abrocitinib - Dermatitis, Atopic | Not yet recruiting | Pfizer | 120 | 2026-10-01 | 2026-10-21 | |
| Randomized Interventional Clinical Trial on the Prevention of Atrial Fibrillation Using Colchicine, Amiodarone And a Posterior Pericardiotomy. Colchicine, Amiodarone, Posterior pericardiotomy - Atrial Fibrillation (AF) | Phase 3 | Not yet recruiting | Elsan | 636 | 2027-01-01 | 2026-10-21 |
| Exercise, Mediterranean Diet and Inflammation in Heart Failure Structured exercise training program, Mediterranean diet counseling, Standard heart failure management - Heart Failure, Heart Failure Preserved Ejection Fraction | Not applicable | Not yet recruiting | Hospital Severo Ochoa | 214 | 2026-11-01 | 2026-10-21 |
| PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial) PATH (Peer Advanced Training for total Health) - Burnout, Secondary Trauma | Not applicable | Enrolling by invitation | Chestnut Health Systems | 200 | 2026-10-12 | 2026-10-21 |
| VATS or Intrapleural Enzymatic Therapy for Patients With Empyema. VATS group, IET - Empyema, Pleural, Pleural Infections | Phase 4 | Not yet recruiting | Amsterdam UMC | 164 | 2026-10-01 | 2026-10-21 |
| Acupuncture for Symptom Burden and Quality of Life in Patients With End-Stage Kidney Disease Acupuncture, Sham Acupuncture - End Stage Kidney Disease (ESKD) | Not applicable | Not yet recruiting | University General Hospital of Heraklion | 160 | 2026-12-01 | 2026-10-21 |
| Nerve Block Resolution Time Display and Pain Complaints Physical display - Postoperative Pain, Rebound Pain | Not applicable | Not yet recruiting | Medical University of South Carolina | 128 | 2026-10-01 | 2026-10-21 |
| Effectiveness of a Music Therapy Intervention in Cancer Patients Undergoing Active Treatment at the Jaén University Hospital: a Non-randomized Controlled Trial. Music Therapy - Anxiety, Signs and Symptoms | Not applicable | Completed | University of Jaén | 120 | 2025-04-01 | 2026-10-21 |
| Acupressure as Complementary Analgesia in Shock Wave Lithotripsy Acupressure, Sham Acupressure - Acupressure, Urinary Calculi | Not applicable | Recruiting | Medipol University | 105 | 2026-10-10 | 2026-10-21 |
| Urinary Catheterization Versus No Catheterization in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair Routine Urinary Catheterization, No Routine Urinary Catheterization - Inguinal Hernias | Not applicable | Active not recruiting | Ugur Duman | 100 | 2026-03-01 | 2026-10-21 |
| AI-SC Multi-center Study evaluate the alignment between AI-SC recommendations and LT-SC decisions, Multi AI-SC model - Liver Cirrhosis | Active not recruiting | University Health Network, Toronto | 1000 | 2026-04-01 | 2026-10-21 | |
| MRD and Imaging Guided Adaptive Neoadjuvant Therapy for Resectable NSCLC PD-1 inhibitor, Carboplatin, Nab-paclitaxel - Non-Small Cell Lung Cancer (NSCLC) | Phase 2 | Not yet recruiting | Peking University People's Hospital | 100 | 2026-11-01 | 2026-10-21 |
| AI-based Algorithm Development for Improved Diagnostics in the Intensive Care and Acute Stroke Setting Using Electroencephalography Hemorrhagic Stroke, Intracerebral, Subarachnoid Haemorrhage (SAH) | Recruiting | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 825 | 2026-03-26 | 2026-10-21 | |
| Gamified Interactive Narrative (REPRO-QUEST) on Sexual Health Literacy and Sexually Transmitted Infection Prevention Behaviors REPRO-QUEST Interactive Narrative, Educational Booklet - Sexual Health, Sexually Transmitted Infection (STI) | Not applicable | Completed | Karamanoğlu Mehmetbey University | 82 | 2026-04-04 | 2026-10-21 |
| COPD Prevalence and Risk Factors Among Saudi Adults Over 18 in Taif Chronic Obstructive Pulmonary Disease (COPD) | Completed | Taif University | 777 | 2024-10-24 | 2026-10-21 | |
| Dose-sparing Balanced Propofol Sedation in Colonoscopy Standard-dose balanced propofol analgosedation, Dose-sparing balanced propofol analgosedation - Colonoscopy, Sedation and Analgesia | Not applicable | Completed | University of Split, School of Medicine | 76 | 2022-06-05 | 2026-10-21 |
| New Treatment in Melasma Tranexamic Acid - topical, Microneedling with Topical Tranexamic acid, Modified Kligman's Formula - Female, With | Not applicable | Not yet recruiting | Sohag University | 75 | 2026-10-18 | 2026-10-21 |
| Reiki After Bariatric Surgery reiki, Sham Reiki - Nausea and Vomitting, Distension; Bowel | Not applicable | Completed | TC Erciyes University | 75 | 2025-11-01 | 2026-10-21 |
| Effects of Respiratory Muscle Strengthening and Diaphragmatic Breathing on Shoulder Pain and Disability shoulder rehabilitation, respiratory muscle strengthening exercises and diaphragmatic breathing exercises - Shoulder Pain, Sleep Quality | Not applicable | Recruiting | Zonguldak Bulent Ecevit University | 70 | 2025-11-25 | 2026-10-21 |
| Telerehabilitation-Supported Exercise in Women With Lipedema Telerehabilitation-Supported Exercise, Home Exercise Program - Lipedema | Not applicable | Not yet recruiting | Istanbul University | 66 | 2026-10-19 | 2026-10-21 |
| EFFECT OF ABDOMINAL MASSAGE TRAINING PROVIDED TO CAREGIVERS ON CONSTIPATION MANAGEMENT Caregiver Training in Abdominal Massage - Constipation | Not applicable | Recruiting | HAMİYET KIZIL | 62 | 2026-09-09 | 2026-10-21 |
| Measured Versus Hemoglobin-Calculated Postpartum Blood Loss in Waterbirth Water immersion during labor and birth - Postpartum Hemorrhage, Waterbirth | Not yet recruiting | University of Campania Luigi Vanvitelli | 600 | 2027-04-01 | 2026-10-21 | |
| EFFECT OF COMBINED VIRTUAL REALITY-GUIDED BREATHING AND AEROBIC TRAINING ON VENTILATORY FUNCTION IN PATIENTS WITH COPD VR-Based Pulmonary Rehabilitation Group, Conventional Pulmonary Rehabilitation Group - Chronic Obstructive Lung Disease | Not applicable | Not yet recruiting | Cairo University | 60 | 2026-11-01 | 2026-10-21 |
| Deep Repetitive Transcranial Magnetic Stimulation in the Treatment of Tinnitus DeepTms - Tinnitus, Tinnitus, Bilateral | Not applicable | Recruiting | University of Regensburg | 60 | 2026-09-19 | 2026-10-21 |
| Photobiomodulation After Nonsurgical Root Canal Treatment Adjunctive Photobiomodulation, Sham Photobiomodulation - Symptomatic Apical Periodontitis, Postoperative Pain | Not applicable | Not yet recruiting | University of Minnesota | 60 | 2026-10-19 | 2026-10-21 |
| Postsurgical Pain and Opioid Use in Older Adults: Effects of Mild Cognitive Impairment Mild Cognitive Impairment (MCI), Opioid Use | Not yet recruiting | Miklos Kertai | 552 | 2027-01-01 | 2026-10-21 | |
| Implementation of Shoulder School in Albania Shoulder school, Standard Care (in control arm) - Rotator Cuff Related Shoulder Pain | Not applicable | Not yet recruiting | University of Valladolid | 50 | 2026-11-01 | 2026-10-21 |
| reALIGNing Circadian Rhythm and Promoting Sleep in the Intensive Care Unit Sleep chronobundle, Control - Sleep, Circadian Dysregulation | Early Phase 1 | Not yet recruiting | University of Alberta | 50 | 2026-11-30 | 2026-10-21 |
| HUGO-SLEEVE: Evaluating the Feasibility of Robotic Sleeve Gastrectomy With a New Platform Sleeve Gastrectomy using Hugo RAS platform - Obesity (BMI > 35), Obesity (BMI > 35) and Diabetes Mellitus | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 50 | 2026-06-04 | 2026-10-21 |
| Study of Grape Consumption in Adaptation to Seasonal Photoperiod Freeze-Dried Grape Powder, Plain Low-Fat Yogurt, Mediterranean-Style Dietary Guidance - Metabolic Dysfunction-Associated Steatotic Liver Disease, Overweight | Not applicable | Active not recruiting | University Rovira i Virgili | 46 | 2026-09-28 | 2026-10-21 |
| Buzzy Bee for Pain and Anxiety Control During Pediatric Dental Local Anesthesia Intervention A: Buzzy® Bee-Assisted Local Anesthesia, Intervention B: Conventional Local Anesthesia Technique - Anesthesia, Anxiety | Not applicable | Recruiting | Tanta University | 40 | 2025-08-01 | 2026-10-21 |
| Effects of Myofascial Release on Postural Balance and Cervical Muscle Function in Benign Paroxysmal Positional Vertigo Home-Based Balance Exercise Program, Myofascial Release Therapy - Benign Paroxysmal Positional Vertigo | Not applicable | Completed | Karabuk University | 40 | 2021-09-01 | 2026-10-21 |
| Functional Electrical Stimulation Combined With Exercise for Rotator Cuff-Related Shoulder Pain in Older Adults Functional electrical stimulation, Sham Functional Electrical Stimulation, Progressive Resistance Training - Rotator Cuff Disease, Subacromial Pain Syndrome | Not applicable | Recruiting | Lisa Griffin | 40 | 2025-10-01 | 2026-10-21 |
| Long Term Outcome After Use of Vacuum-induced Tamponade for Postpartum Hemorrhage Postpartum Hemorrhage, Treatment Outcome | Recruiting | University of Zurich | 380 | 2026-10-01 | 2026-10-21 | |
| Cannabidiol in Opioid Use Disorder and Chronic Pain With Buprenorphine 400 mg Cannabidiol, 800 mg Cannabidiol, 1200 mg Cannabidiol - Chronic Pain, Opioid Use Disorder | Early Phase 1 | Recruiting | Yale University | 34 | 2021-12-08 | 2026-10-21 |
| Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft Z-Plasty, Full-Thickness Skin Graft - Joint Contracture, Contracture | Not yet recruiting | Universitas Sebelas Maret | 300 | 2026-10-13 | 2026-10-21 | |
| Tacabrutideg and Sonrotoclax, With Response-Guided Obinutuzumab, for the Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) Tacabrutideg, Sonrotoclax, Obinutuzumab - Chronic Lymphocytic Leukemia, Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | Phase 2 | Not yet recruiting | Fred Hutchinson Cancer Center | 30 | 2027-01-01 | 2026-10-21 |
| Safety of Anticoagulation Therapy in Cirrhotic Patients With PVT and Severe Thrombocytopenia Anticoagulation Therapy - Thrombocytopenia Related to Chronic Liver Disease, Anticoagulation Treatment | Completed | Qilu Hospital of Shandong University | 304 | 2025-09-01 | 2026-10-21 | |
| 68Ga-XMFH01 PET/Fluorescence Imaging in Prostate Cancer 68Ga-XMFH01 PET/CT - Prostate Cancer (Diagnosis), ACP3 | Not applicable | Recruiting | The First Affiliated Hospital of Xiamen University | 25 | 2026-10-21 | 2026-10-21 |
| Perfusion Efficiency-Guided MAP De-escalation in Elderly Septic Shock Ascending MAP titration sequence, Descending MAP titration sequence - Sepsis | Not applicable | Not yet recruiting | Peking Union Medical College Hospital | 24 | 2026-11-01 | 2026-10-21 |
| Circuit Breathing Exercise on Smoking Cessation Among Youth E-Cigarette Users Circuit breathing, Diaphragmatic Breathing, Normal Breathing Condition - E Cigarette Use | Not applicable | Recruiting | Chulalongkorn University | 20 | 2026-08-15 | 2026-10-21 |
| Hypoglycemia Risk Assessment in Elderly and Senile Female Patients With Type 2 Diabetes Mellitus Comprehensive Geriatric Assessment, Sarcopenia assessment, Laboratory assessment - Type 2 Diabetes Mellitus, Hypoglycemia | Completed | Samara State Medical University | 200 | 2020-01-01 | 2026-10-21 | |
| Manual Acupuncture for Intradialytic Fatigue in CKD Patients Manual Acupuncture, Sham Acupuncture - Intradialytic Fatigue, Chronic Kidney Disease | Not applicable | Not yet recruiting | Universitas Indonesia | 19 | 2026-10-01 | 2026-10-21 |
| Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone Dynamics Cardiogenic Shock, Euthyroid Sick Syndrome | Recruiting | Gottsegen National Cardiovascular Institute | 160 | 2026-08-17 | 2026-10-21 | |
| Efficacy and Safety of Modafinil to Treat Fatigue in People With Mitochondrial Disease. Modafinil (Placebo) - Mitochondrial Disease | Phase 3 | Not yet recruiting | Kenneth Myers, MD | 15 | 2026-12-01 | 2026-10-21 |
| Whole-Body Point-of-Care Ultrasound in Older Adults Presenting to the Emergency Department After a Fall Whole-body point-of-care ultrasound (POCUS) - Accidental Falls, Aged | Recruiting | Kocaeli City Hospital | 105 | 2026-10-12 | 2026-10-21 | |
| Clinical, Functional, and Therapeutic Characterization of Women With Urinary Incontinence and Analysis of Factors Associated With Treatment Response Artificial intelligence clinical decision support model - Urinary Incontinence (UI) | Not yet recruiting | Javier Pereira | 80 | 2026-12-01 | 2026-10-21 | |
| Enteral Feeding in Mechanically Ventilated Children Critical Illness, Mechanical Ventilation Complication | Not yet recruiting | Assiut University | 60 | 2026-10-26 | 2026-10-21 | |
| Deep Brain Stimulation Guided by Brain Mapping to Treat Cognitive Impairment Abbott St Jude Medical Infinity™ - Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Amnestic | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 6 | 2026-11-01 | 2026-10-21 |
| Dexmedetomidine for Refractory Pain in Palliative Cancer Patients Cancer, Palliative Care, Patient Care | Recruiting | St. Olavs Hospital | 30 | 2026-04-10 | 2026-10-21 | |
| Real-World Use of Tarlatamab in Chinese Patients With Small-Cell Lung Cancer Tarlatamab - Extensive-Stage Small Cell Lung Cancer | Active not recruiting | Ruijin Hospital | 26 | 2026-08-03 | 2026-10-21 | |
| Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study Nasal High Flow, Continuous Positive Airway Pressure - Chronic Obstructive Pulmonary Disease (COPD) | Not yet recruiting | Klinikum Dortmund Wirbelsäulenchirurgie | 20 | 2026-10-01 | 2026-10-21 |