Enteral Feeding in Mechanically Ventilated Children

NCT07884838 — Not yet recruiting, 60 participants, Assiut University

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Enteral Feeding Practices and Nutritional Adequacy in Mechanically Ventilated Children

Registry	NCT07884838
Status	Not yet recruiting
Study type	Observational
Enrollment	60 (Estimated)
Sponsor	Assiut University (Other)
Conditions	Critical Illness, Mechanical Ventilation Complication
Dates	start 2026-10-26 (estimated), primary completion 2027-10-26 (estimated), completion 2028-02-10 (estimated), first posted 2026-10-21, last updated 2026-10-21

-Summary

This prospective cohort study aims to assess enteral feeding practices and the adequacy of energy and protein delivery among mechanically ventilated children admitted to the pediatric intensive care unit.

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+Detailed description

Children requiring invasive mechanical ventilation in the pediatric intensive care unit are at high risk of inadequate energy and protein intake. Enteral nutrition is preferred when the gastrointestinal tract is functional.

This observational study will prospectively evaluate the timing of initiation, adequacy of energy and protein delivery, feeding interruptions, and selected clinical outcomes in mechanically ventilated children admitted to the PICU at Assiut University Children's Hospital.

+Arms and interventions

Arm	Type	Interventions	Description
Mechanically Ventilated Children			Children aged 1 month to 18 years requiring invasive mechanical ventilation in the PICU who will be followed for enteral feeding practices and nutritional adequacy.

+Outcome measures

Primary outcomes

Number of children achieving adequate energy delivery [At 7 days]: Number of mechanically ventilated children who achieve predefined adequate energy delivery during the assessment period.

Secondary outcomes

Energy adequacy percentage [At 7 days]: Mean energy adequacy calculated as actual energy received divided by estimated energy requirement multiplied by 100.
Time to initiation of enteral feeding [At 7 days]: Mean time in hours from PICU admission to initiation of enteral feeding.
Duration of mechanical ventilation [At 28 days]: Mean duration of invasive mechanical ventilation in days.
PICU length of stay [At 28 days]: Mean length of stay in the pediatric intensive care unit in days.

+Eligibility

Sex: All, ages: 1 Month to 18 Years

Inclusion Criteria:

* \- Children aged 1 month to 18 years
* Admission to the PICU
* Requirement for invasive mechanical ventilation
* Expected PICU stay sufficient for assessment of nutritional delivery
* Written informed consent from parent or legal guardian

Exclusion Criteria:

* \- Neonates under 1 month of age
* Absolute contraindication to enteral feeding
* Exclusive parenteral nutrition from admission
* Death or transfer within 48 hours of admission
* Inborn errors of metabolism needing special diets

+Investigators

Ismail L Mohammed, prof, Study chair, Pediatrics Department, Assiut University Hospitals