Presence of Barrett's Esophagitis in a Cohort of People With Eating Disorders Who Engage in Purging Behaviors: A Pilot Study
| Registry | NCT06532734 |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Enrollment | 25 (Estimated) |
| Sponsor | Denver Health and Hospital Authority (Other); collaborators: Lucid Diagnostics, Inc. |
| Conditions | Barrett Esophagus, Anorexia Nervosa, Binge Eating/Purging Type, Rumination, Vomiting, Eating Disorders, Esophageal Adenocarcinoma |
| Interventions | EsoGuard (Device) |
| Dates | start 2024-11-12, primary completion 2026-11-01 (estimated), completion 2026-11-01 (estimated), first posted 2024-08-01, last updated 2025-12-10 |
| Locations | 3 sites in United States |
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All trials for Barrett Esophagus All trials for Anorexia Nervosa, Binge Eating/Purging Type All trials of EsoGuard
To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors
A prospective cohort study to assess the presence of BE in those with purging behaviors from their eating disorders has not been completed. There are multiple case reports describing a younger population not meeting typical screening guidelines whom developed this condition. To better define the presence of Barrett's esophagus (BE) via non-endoscopic testing in an eating disorder cohort with purging (vomiting/rumination) behaviors. Individuals with severe forms of eating disorders with purging and ruminating behaviors not meeting the current screening guidelines for BE will still test positive for BE.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| AN-BP | Device: EsoGuard | individuals with a dx of AN-BP, with a >5-year history of purging, with a frequency of at least once a day. |
Sex: All, ages: 18 Years to 65 Years
Inclusion Criteria: * Patients diagnosed with an eating disorder diagnosis that includes purging history * Ages 18-65 * Purging history =>5 years * Purging or rumination at a minimum of once daily upon admission. * Admission to the ACUTE Center for Eating Disorders and Severe Malnutrition Exclusion Criteria: * Any eating disorder diagnosis that does not include purging behaviors * Ages under 18 and over 65 * Patients who otherwise meet the current ACG screening guidelines (chronic GERD and 3 or more risk factors for Barrett's mentioned in the Background) * Received mandated care at time of enrollment * Inability to consent to participate in the research
| Facility | City | Country | Status |
|---|---|---|---|
| ACUTE Center for Eating Disorders and Severe Malnutrition | Denver, Colorado | United States | Recruiting |
| Denver Health and Hospital Authority | Denver, Colorado | United States | Recruiting |
| Denver Health and Hospital Authority | Denver, Colorado | United States | Recruiting |