A Longitudinal Study for Identifying Predictors of Incidence/Remission of Probable Depression and Developing a Predictive Index for Probable Depression Among Secondary School Students
| Registry | NCT04063202 |
|---|---|
| Status | Unknown |
| Study type | Observational |
| Enrollment | 4799 (Estimated) |
| Sponsor | Chinese University of Hong Kong (Other) |
| Conditions | Depression, Stress, Youth |
| Interventions | Observation (Other) |
| Dates | start 2020-10-30, primary completion 2023-08-01 (estimated), completion 2023-08-01 (estimated), first posted 2019-08-21, last updated 2022-03-17 |
| Locations | 4 sites in Hong Kong |
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The present study aims to develop a new predictive index to predict future depression of adolescents by using factors including individual, interpersonal and environmental. The index can be used to predict likelihood of students who are non-probable depression cases convert into probable depression cases. In addition, the investigators also test the factors of depression remission. It can hence be used in school setting to identify high-risk students, and provide them with secondary interventions that are designed by considering modifiable significant variables identified in this unique, large-scale, longitudinal study.
A 12-month longitudinal study will be conducted in secondary school settings.
The investigators will investigate incidence of probable depression (i.e., from non-depression, CESD<16, at baseline to probable depression, CESDā„16, at month 12) and remission of probable depression.
The investigators will investigate factors that can prospectively predict new cases/remission of probable depression, including both well-documented risk/protective factors and some under-examined but potentially important local factors (e.g. school/academic stress, psychological resilience). The relative importance of the risk/protective factors at different socio-ecological levels will be compared and their combined effect will be identified.
Based on the selected factors, the investigators will derive a new prediction index called the Adolescent Depression Prediction Index (ADPI) in a model building sample and test its performance in predicting incidence of depression in a validation sample among secondary school students in Hong Kong.
| Arm | Type | Interventions | Description |
|---|---|---|---|
| Non-cases | Other: Observation | Secondary school students (seventh to tenth years of education) without probable depression at baseline interview. |
Sex: All, ages: 12 Years to 16 Years
Inclusion Criteria: * Secondary 1 (seventh year of formal education) to Secondary 4 Chinese students, who are studying local mainstream schools in Hong Kong. * Able to read Chinese and speak either Cantonese or Mandarin. Exclusion Criteria: * Eligible students whose parents refuse to give consent to take part in the study.
| Facility | City | Country | Status |
|---|---|---|---|
| China Holiness Church Living Spirit College | Hong Kong | Hong Kong | Recruiting |
| Christian Alliance SW Chan Memorial College (Christian Alliance SW Chan Memorial Secondary School) | Hong Kong | Hong Kong | Recruiting |
| Ho Ngai College ( Sponsored By Sik Sik Yuen) | Hong Kong | Hong Kong | Recruiting |
| Kit Sam Lam Bing Yim Secondary Schoo | Hong Kong | Hong Kong | Recruiting |