Protocoled Quantitative Assessment of Aortic Regurgitation Using Videodensitometry in a Multicontinental Trial in Rotterdam, Montreal, Yamaguchi, Segeberg, Amsterdam.

• Standardized protocol for assessing aortic regurgitation using videodensitometry (Diagnostic test): Standardized protocol for assessing aortic regurgitation using videodensitometry

Primary outcomes

• Feasibility (percentage of the cases considered analyzable) of analysis of aortic regurgitation from aortograms using the videodensitometry technique [1 year]: Measurement of feasibility, i.e. the percentage of the number of cases, out of the entire sample size that are considered to be analyzable for quantitative aortic regurgitation assessment using videodensitometry after the implementation of the acquisition protocol. Since the analyzability of the aortic regurgitation from the aortograms depends in some acquisition factors, we will assess the feasibility of analysis after implantation of acquisition protocols.

Sex: All, ages: 18 Years to any

Inclusion Criteria:

* Eligible and undergoing TAVR procedure

Exclusion Criteria:

* Considered not eligible for TAVR procedure by the local Heart Team

• Results publication: Modolo R, Chang CC, Tateishi H, Miyazaki Y, Pighi M, Abdelghani M, Roos MA, Wolff Q, Wykrzykowska JJ, de Winter RJ, Piazza N, Richardt G, Abdel-Wahab M, Soliman OII, Onuma Y, Van Mieghem NM, Serruys PW. Quantitative aortography for assessing aortic regurgitation after transcatheter aortic valve implantation: results of the multicentre ASSESS-REGURGE Registry. EuroIntervention. 2019 Aug 29;15(5):420-426. doi: 10.4244/EIJ-D-19-00362. PMID 31147307

• Patrick W Serruys, MD, PhD, Study chair, Imperial College London
• Rodrigo Modolo, MD, Principal investigator, Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
• Yoshinobu Onuma, MD, PhD, Principal investigator, Erasmus Medical Center