Effect of Low-level Laser Therapy on Post-bleaching Sensitivity and Color Change

NCT03514290 — Not applicable, Completed, 21 participants, Universidade Federal do Para

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Effect of Low-level Laser Therapy on Post-bleaching Sensitivity and Color Change: a Clinical, Randomized and Double-blind Study

RegistryNCT03514290
StatusCompleted
PhaseNot applicable
Study typeInterventional; randomized, crossover, masking: double, treatment
Enrollment21 (Actual)
SponsorUniversidade Federal do Para (Other)
ConditionsTooth Bleaching, Low-level Laser Therapy, Dentin Sensitivity, Clinical Trial
InterventionsLow-lever laser, Tooth bleaching, Placebo (Radiation, other)
Datesstart 2016-07-11, primary completion 2016-08-08, completion 2016-09-30, first posted 2018-05-02, last updated 2018-05-02
Locations1 site in Brazil

Related Papers Related Patents Related Grants Related Experts
All trials for Tooth Bleaching All trials for Low-level Laser Therapy All trials of Low-lever laser All trials of Tooth bleaching

-Summary

Objective: The objective of this clinical study was to evaluate low-level laser (LLL) therapy in tooth sensitivity and in effecting color change after in-officer bleaching treatment across three weeks of treatment.

Methods: Twenty-one volunteers were evaluated through the split-mouth model, so that the right and left maxillary/mandibular quadrants were randomized and allocated to one of two groups: GPLACEBO - the laser tip was positioned without the emission of light (placebo effect) + tooth bleaching with 35% hydrogen peroxide (HP); GLASER - treated with LLL + tooth bleaching with 35% HP. To assess tooth sensitivity, a modified visual analogue scale (VAS) was used after an evaporative stimulus (stimulated pain) and a daily pain questionnaire (unstimulated pain) was also applied. A spectrophotometer was used to measure the color. Three bleaching sessions were performed, with intervals of 7 days. Sensitivity results were tested using Friedman test for intra-group evaluation and Wilcoxon test for inter-group evaluation and ANOVA for color change.

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+Detailed description

Twenty-one volunteers were evaluated through the split-mouth model, so that the right and left maxillary/mandibular quadrants were randomized and allocated to one of two groups: GPLACEBO - the laser tip was positioned without the emission of light (placebo effect) + tooth bleaching with 35% hydrogen peroxide (HP); GLASER - treated with LLL + tooth bleaching with 35% HP. To assess tooth sensitivity, a modified visual analogue scale (VAS) was used after an evaporative stimulus (stimulated pain) and a daily pain questionnaire (unstimulated pain) was also applied. A spectrophotometer was used to measure the color. Three bleaching sessions were performed, with intervals of 7 days.

+Arms and interventions

ArmTypeInterventionsDescription
GPLACEBOPlacebo comparatorOther: Tooth bleaching; Other: Placebothe laser tip was positioned without the emission of light (placebo effect) + tooth bleaching with 35% hydrogen peroxide (HP).
GLASERExperimentalRadiation: Low-lever laser; Other: Tooth bleachingtreated with Low-lever laser + tooth bleaching with 35% hydrogen peroxide (HP).
  • Low-lever laser (Radiation), also known as Laserterapy: Received Low-lever laser therapy using the infrared spectrum, with a wavelength of 808 nm in its active medium AsGaAl (arsenic-gallium-aluminum), at two points: on the central of cervical and medial regions of incisors, canines and premolars in the corresponding hemi-arch. At each point, 60 J/cm2 was applied during 16 seconds with an irradiance of 3.75 W/cm² using the therapeutic visible infrared device.
  • Tooth bleaching (Other): Three 15-minute applications of 35% hydrogen peroxide gel (Whiteness HP, FGM®, Joinville, SC, Brazil) were carried out, totaling 45 minutes in each of the four bleaching sessions, with an one-week interval between applications.
  • Placebo (Other): The laser tip was positioned similarly to experimental group but without light irradiation

+Outcome measures

Primary outcomes

  • Dental sensitivity induced by office bleaching [change in baseline sensitivity at the 3rd bleaching session]: Evaporative stimulus (stimulated pain) using air jet from a triple syringe and a daily pain questionnaire (unstimulated pain). Both methods were associated with a modified visual analogue scale was used: 0 (pain absent); 1 (mild pain); 2 (moderate pain) and 3 (severe pain).

Secondary outcomes

  • Color change promoted by tooth bleaching [change in baseline color at the 3rd bleaching session]: Spectrophotometer was used to measure the color

+Eligibility

Sex: All, ages: 18 Years to 30 Years, accepts healthy volunteers

Inclusion Criteria:

* Do not have previous dental sensitivity
* The canine had to be shade A2 or darker.

Exclusion Criteria:

* Enamel hypoplasia
* Gingival recession
* Dentin exposure
* Visible cracks on buccal enamel
* Pulpitis

+Locations (1)

FacilityCityCountryStatus
Federal University of ParáBelém, ParáBrazil

+Investigators

  • Cecy M Silva, Principal investigator, Federal University of Para