Acute Postthoracotomy Pain - Impact of Gender

NCT03281213 — Completed, 346 participants, Medical University of Graz

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No Impact of Gender on Acute Postthoracotomy Pain - a Retrospective Analysis

RegistryNCT03281213
StatusCompleted
Study typeObservational
Enrollment346 (Actual)
SponsorMedical University of Graz (Other)
ConditionsGender, Postoperative Pain, Thoracotomy, Analgesia
InterventionsThoracotomy (Other)
Datesstart 2010-07-01, primary completion 2014-12-31, completion 2016-06-01, first posted 2017-09-13, last updated 2017-09-13
Locations1 site in Austria

Related Papers Related Patents Related Grants Related Experts
All trials for Gender All trials for Postoperative Pain All trials of Thoracotomy

-Summary

Adequate analgesia in thoracic surgery is essential to prevent severe postoperative complications, especially respiratory problems. Current knowledge about gender-related differences in pain states generally more frequent and intense pain and more demand for analgesics in women. Results about postsurgical pain in particular are very inconclusive.

The investigators tried to find out if gender has an influence on postthoracotomy pain and analgesics requirement.

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+Arms and interventions

ArmTypeInterventionsDescription
FemaleOther: Thoracotomy
MaleOther: Thoracotomy
  • Thoracotomy (Other)

+Outcome measures

Primary outcomes

  • Visual Analogue Scores [first 5 postoperative days]
  • Analgesics requirement [first 5 postoperative days]

+Eligibility

Sex: All, ages: 18 Years to any, accepts healthy volunteers

Inclusion Criteria:

* open lung surgery between July 2010 and December 2014

Exclusion Criteria:

* redo-thoracotomy
* chest wall or rib resection
* other approach than lateral thoracotomy
* additional incision at other site (e.g. laparotomy)
* chest trauma
* mesothelioma
* hemofiltration or haemodialysis
* longer than one day stay at intensive care unit
* pre-existent chronic pain and/or chronic opioid intake
* short stay in hospital

+Locations (1)

FacilityCityCountryStatus
Medical University of Graz, Division of Thoracic and Hyperbaric SurgeryGraz, StyriaAustria

+Publications

  • Results publication: Auinger D, Sandner-Kiesling A, Striessnig A, Lindenmann J, Smolle J, Friedl H, Smolle-Juttner FM. Is There an Impact of Sex on Acute Postthoracotomy Pain? A Retrospective Analysis. Ann Thorac Surg. 2020 Apr;109(4):1104-1111. doi: 10.1016/j.athoracsur.2019.11.016. Epub 2019 Dec 28. PMID 31891695

+Investigators

  • Daniel Auinger, MD, Principal investigator, Medical University of Graz
  • Freyja-Maria Smolle-Jüttner, Study director, Medical University of Graz