Study of Yili "Changqing" Pro-ABB Yoghurt in the Improvement of Human Gastrointestinal Tract System

• Placebo yoghurt (Dietary supplement): 100g of placebo yoghurt will be taken at 10:00 am and 4:00 pm, respectively; 2 times per day.
• Yili "Chang Qing" Pro-ABB yoghurt (Formula 1) (Dietary supplement): 100g of Yili "Chang Qing" Pro-ABB yoghurt will be taken by at 10:00 am and 4:00 pm, respectively; 2 times per day.
• Yili "Chang Qing" Pro-ABB yoghurt (Formula 2) (Dietary supplement), also known as 100g of Yili "Chang Qing" Pro-ABB yoghurt will be taken by at 10:00 am and 4:00 pm, respectively; 2 times per day.

Primary outcomes

• Change in constipation condition after 3 weeks [Baseline & 3 weeks]

Secondary outcomes

• Change in gut resident flora after 3 weeks [Baseline & 3 Weeks]

Sex: All, ages: 25 Years to 45 Years, accepts healthy volunteers

Inclusion Criteria:

1. Male or female subjects, 25-45 yrs;
2. Non-specific and/or moderate constipation;
3. Irregular or occasional gastrointestinal disorders (flatulence, gurgling, feeling heavy after eating, abdominal pain);
4. Slow transit or irregular bowels movements (abnormal feces solidity, bowel movements decreased, e.g. every 2-3 days or less than 3 times per week).

Exclusion Criteria:

1. Diagnosed as chronic constipation;
2. Treated gastrointestinal symptoms;
3. Lactose Intolerance;
4. Treatment by analgesic such as aspirin and paracetamol;
5. Had laxatives or other remedies to promote digestion 2 weeks prior to the study start;
6. Consuming dairy products or supplements containing pro/pre-biotic 10 days prior to the study start;
7. Currently suffering from diarrhea.

• Ying An, Ph.D, Study director, Inner Mongolia Hilo Industrial Group Co., Ltd
• Donglian Cai, Principal investigator, Changhai Hospital of Shanghai, Nutriology Dept.
• Xinwang Gao, Principal investigator, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Geriatric Medicine Dept..