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Bioengineering Papers of the Week

The 20 most important new Bioengineering papers of the past week, ranked by potential impact. A new issue comes out every Monday, covering the previous Monday-to-Sunday week.

Nov 2 - 8, 2026 · Updated

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    Continual Learning in Medical Imaging: A Systematic Review of Methods, Applications, and Clinical Translation

    Following PRISMA 2020, we searched five sources with database-specific search strings and included 77 primary studies.

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  1. 6
    Precision Fermentation for Next Generation Food Ingredients: Technological Foundations, Food Applications, Sustainability, and Regulatory Challenges

    However, the scientific and industrial promise of precision fermentation should not be presented as unconditional, because its real sustainability, safety, affordability, and scalability depend on microbial host selection, feedstock source, fermentation productivity, downstream processing efficiency, energy input, regulatory approval, and consumer acceptance. Therefore, this review critically discusses the evolution of precision fermentation from traditional fermentation, its technological basis, major food applications, food safety assessment requirements, environmental and techno‐economic considerations, regulatory landscapes, consumer acceptance, and future research needs.

  2. 7
    Chitosan and Aloe Vera-based Biomaterials for Wound Healing Applications

    This work critically evaluates the synergistic integration of chitosan (CS) and aloe vera (AV) into advanced wound dressings.

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    [Reliability-aware Periodicity Graph Neural Network for Remote Heart Rate Estimation]

    Conventional periodic modeling methods typically assign equal weights to graph-structured temporal segments, thereby overlooking differences in node reliability and temporal variations in signal quality. To address this limitation, this paper proposes a reliability-aware periodic graph neural network for robust rPPG estimation.

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    Nanoengineered Biomaterials Manipulating Lymph Nodes for Effective Cancer Immunotherapy

    We highlight two delivery routes, namely passive drainage and active targeting, and discuss how biomaterials achieve the spatiotemporal coordination of dendritic-cell activation, major histocompatibility complex class I cross-presentation, and T cell priming within lymph nodes.

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    Structure-property Relationships in A Graphene Oxide-reinforced Chitosan-carboxymethylcellulose-alginate Composite for Wound Dressing Applications

    In this study, graphene oxide (GO)-functionalized chitosan-carboxymethylcellulose-alginate (ChitCMCAlgGO) sponge scaffolds were developed to investigate the role of GO in modulating the molecular organization and functional properties of a multicomponent polysaccharide network.

  9. 14
    Defining The Operating Envelope of Camera-Based Optical Character Recognition for Structured Data Capture from Non-Interoperable ICU Bedside Device Displays: A Controlled Technical Validation Study

    We evaluated a frame-sampled pipeline comprising display localisation, segmentation, pre-processing, OCR, clinical dictionary-based normalisation, and layered quality-control gating.

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    Engineering Electro-Regenerative Microenvironment for Bone Repair: Advances in Electroactive Biomaterials

    Inspired by these physiological mechanisms, increasing research efforts have focused on engineering electroactive biomaterials to modulate local bioelectrical cues and establish regenerative microenvironments conducive to bone repair. In this context, we propose the concept of the electro-regenerative microenvironment (ERM), which emphasizes the regulation of interconnected biological processes, including antibacterial activity, immunomodulation, angiogenesis, neurogenesis, and osteogenesis, through bioelectrical cues mediated by electroactive biomaterials.

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    Constitutive Modeling of Degradation‐Induced Mechanical Behavior in Commercial Polydioxanone for Implantable Devices

    ABSTRACT In this study, the mechanical behavior of a commercially available polydioxanone (RESOMER X 206S, Evonik) and its evolution under in vitro degradation were investigated through combined experimental and constitutive modeling approaches.

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    Nitrogen-doped Carbon Dots for Combating Bacterial Infections Via Synergistic Membrane Disruption and Biofilm Eradication

    In this work, a series of N-CDs with varying nitrogen doping levels (0%–20%) were synthesized via a one-step hydrothermal method using D-sorbitol and L-lysine as precursors, targeting the growing challenge of bacterial infections.

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    Piezoelectric Dental Resin Composites for Mastication-induced Antibacterial Restorations: A Critical Review

    This review discusses representative piezoelectric materials, including barium titanate (BaTiO₃) and zinc oxide (ZnO), with particular emphasis on their mechanical-to-electrical energy conversion behavior and the mechanisms underlying their antibacterial and antibiofilm effects and their promotion of dentin remineralization.

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    Re-timing Mortality Risk Through Individualized Modelling of Lifespan Trajectories

    Using low-cost, non-invasive retinal photographs and leveraging large foundation models, we developed a deep learning-based biomarker, Retinal Mortality Equivalent (RetiME), that directly mapped retinal features to individual mortality risk.

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    A Single-step Injectable Janus-adhesive Hydrogel for Endoscopic Gastrointestinal Fistula Repair

    Here we develop a thermoresponsive positively charged poly(N-isopropylacrylamide) (PNIPAM)/Ga (PGa ) hydrogel sealant, formed by slug-inspired biomimetic self-assembly.