3 completed, 2 active not recruiting. 3 Phase 2, 2 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 3 | Active not recruiting 2, Completed 1 |
| Phase 1 | 2 | Active not recruiting 2 |
| Phase 3 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PDE6A Gene Therapy for Retinitis Pigmentosa subretinal injection of rAAV.hPDE6A - Retinitis Pigmentosa | Phase 1 / Phase 2 | Active not recruiting | STZ eyetrial | 9 | 2019-09-24 | 2024-04-18 |
| THOR - Tübingen Choroideremia Gene Therapy Trial rAAV2.REP1 - Choroideremia | Phase 2 | Completed | STZ eyetrial | 6 | 2016-01-01 | 2020-10-27 |
| Safety and Efficacy of rAAV.hCNGA3 Gene Therapy in Patients With CNGA3-linked Achromatopsia rAAV.hCNGA3 - Achromatopsia | Phase 1 / Phase 2 | Active not recruiting | STZ eyetrial | 13 | 2015-11-01 | 2024-04-18 |
| Clinical Characterization on PDE6A-related Retinitis Pigmentosa in Preparation to a Gene Therapy Trial Retinitis Pigmentosa | Completed | STZ eyetrial | 50 | 2013-01-01 | 2025-05-18 | |
| Myfortic for the Treatment of Non-infectious Intermediate Uveitis Myfortic, Decortin - Uveitis, Intermediate | Phase 3 | Completed | STZ eyetrial | 44 | 2010-03-01 | 2017-05-09 |
Retinitis Pigmentosa (2) · Choroideremia (1) · Color Vision Defects (1) · Uveitis, Intermediate (1)
Genetic Therapy (1) · Mycophenolic Acid (1) · Prednisolone (1) · Prednisone (1)
Germany (5)
Dominik Fischer, Prof. (2) · Christoph Deuter, Dr. (1) · Ditta Zobor, MD, PhD (1) · Manuel D Fischer, MD, PhD (1) · Susanne Kohl, PhD (1)
PMID 31465092, PMID 32352493, PMID 34006508, PMID 39878701
2009 (1), 2014 (1)