2 terminated, 1 completed, 1 withdrawn. 3 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 3 | Completed 1, Terminated 1, Withdrawn 1 |
| Phase 2 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intratumorally-Administered Topotecan Using CED in High Grade Glioma Undergoing Stereotactic Biopsy Topotecan (<=8cc), Topotecan (>8cc), Cleveland Multiport Catheter - Glioma | Early Phase 1 | Withdrawn | Michael Vogelbaum, MD, PhD | 2017-11-03 | 2019-03-01 | |
| Topotecan in Glioma Undergoing A Clinically-Indicated Surgical Resection topotecan, Cleveland Multiport Catheter - Brain Tumor, High Grade Glioma | Early Phase 1 | Terminated | Michael Vogelbaum, MD, PhD | 9 | 2015-07-06 | 2019-03-01 |
| Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma Topotecan, Gadolinium DTPA, Cleveland Multiport Catheter - Malignant Glioma, WHO Grade III or IV Recurrent Glioma | Early Phase 1 | Completed | Michael Vogelbaum, MD, PhD | 3 | 2014-12-09 | 2017-03-31 |
| Aminolevulinic Acid in Visualizing a Tumor During Surgery in Patients With Glioblastoma Multiforme aminolevulinic acid, therapeutic conventional surgery - Adult Giant Cell Glioblastoma, Adult Glioblastoma | Phase 2 | Terminated | Michael Vogelbaum, MD, PhD | 8 | 2012-05-01 | 2018-07-31 |
Glioma (3) · Brain Neoplasms (2) · Glioblastoma (1) · Gliosarcoma (1) · Lymphoma, Follicular (1) · Neoplasms (1)
Topotecan (3) · Aminolevulinic Acid (1) · Gadolinium DTPA (1) · Magnetic Resonance Imaging (1)
United States (3)
Michael A Vogelbaum, MD, PhD (2) · Michael A. Vogelbaum, MD, PhD (1)