2 active not recruiting, 2 recruiting, 1 completed, 1 not yet recruiting. 4 Not applicable, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Active not recruiting 1, Completed 1, Recruiting 1, Unknown 1 |
| Phase 3 | 2 | Active not recruiting 1, Withdrawn 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mechanistic 129 Xe MRI Study to Assess Therapeutic Response in Fibrotic Interstitial Lung Disease Hyperpolarized 129Xe MRI - Fibrotic Interstitial Lung Disease | Not yet recruiting | Dr. Grace Parraga | 35 | 2026-11-01 | 2026-08-28 | |
| PAXT: Pulmonary Imaging of Mild Asthma Using 129Xe MRI and Tc-99-Labeled-Carbon-Imaging (Tc99CImaging) Hyperpolarized 129Xe MRI, Tc-99m Technegas Ventilation Imaging - Mild Asthma | Recruiting | Dr. Grace Parraga | 40 | 2026-03-02 | 2026-07-31 | |
| Evaluation of Triple Therapy Using Magnetic Resonance Imaging in Asthma FF/UMEC/VI - Asthma | Phase 3 | Active not recruiting | Dr. Grace Parraga | 31 | 2022-08-08 | 2025-08-29 |
| Evaluating the Effect of Benralizumab in Severe, Poorly-controlled Eosinophilic Asthma Using Inhaled Hyperpolarized 129-Xenon MRI Benralizumab, 129 Xenon - Asthma; Eosinophilic | Not applicable | Active not recruiting | Dr. Grace Parraga | 29 | 2022-03-01 | 2025-08-11 |
| Investigating the Effects of QVM149 on MRI Ventilation Defects QVM149, High Dose Dual Therapy (ICS/LABA) - Asthma | Phase 3 | Withdrawn | Dr. Grace Parraga | 2021-12-01 | 2021-12-14 | |
| Structure and Function MRI of Asthma Hyperpolarized Noble Gas MRI - Asthma | Not applicable | Recruiting | Dr. Grace Parraga | 200 | 2015-01-01 | 2026-07-31 |
| Hyperpolarized Magnetic Resonance Imaging in Asthma Pre- and Post-Bronchial Thermoplasty Conventional Bronchial Thermoplasty, Image Guided Bronchial Thermoplasty - Asthma | Not applicable | Completed | Dr. Grace Parraga | 25 | 2014-10-01 | 2023-05-12 |
| Longitudinal Study of Helium-3 and Xenon-129 Magnetic Resonance Imaging Hyperpolarized Helium MRI - COPD, Bronchiectasis | Not applicable | Unknown | Dr. Grace Parraga | 200 | 2009-05-01 | 2024-06-13 |
Asthma (4) · Bronchiectasis (1) · Pulmonary Disease, Chronic Obstructive (1) · Pulmonary Eosinophilia (1)
benralizumab (1) · indacaterol (1)
Canada (8)
Grace E Parraga, PhD (7) · David G McCormack, MD (1) · Grace E Parraga, PHD (1)
PMID 33289613, PMID 36781102, PMID 27174885, PMID 31895987, PMID 32096708, PMID 35283104, PMID 37395048, PMID 37737132, PMID 39221567, PMID 42301257