4 completed, 3 unknown, 1 terminated. 3 Not applicable, 2 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Completed 2, Unknown 1 |
| Phase 4 | 2 | Completed 1, Unknown 1 |
| Phase 1 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin Dolutegravir - Hiv, Tuberculosis | Phase 4 | Completed | Helen Reynolds | 36 | 2021-11-18 | 2024-08-13 |
| A Comprehensive HIV Prevention Package for South African Adolescent Girls and Young Women: IMARA SA IMARA-SA (intervention group), Health promotion control group - Sexually Transmitted Infection, Hiv | Not applicable | Completed | University of Illinois at Chicago | 61 | 2019-10-26 | 2025-08-22 |
| The Community PrEP Study to Assess the Acceptance of PrEP Delivered Through CBCT Platforms Group-based Community Health Club, Individual-based Adherence Support - PrEP, HIV Prevention | Not applicable | Completed | Foundation for Professional Development (Pty) Ltd | 480 | 2018-10-26 | 2025-04-27 |
| Clinical Evaluation of Adjusted Doses of Darunavir/Ritonavir With Rifampicin in HIV-infected Volunteers Darunavir/ritonavir 800/100 mg tablet, Rifampicin 600mg QD tablet and DTG 50mg BD - HIV Infections | Phase 1 | Terminated | University of Cape Town | 17 | 2018-04-12 | 2019-04-03 |
| 3Ps for Prevention Study (Perception, Partners, Pills) Incentivised - Conditional Cash Transfer, Truvada 200Mg-300Mg Tablet - Adherence | Phase 4 | Unknown | Desmond Tutu HIV Centre | 200 | 2017-03-24 | 2019-02-15 |
| A Study to Evaluate the Acceptability and Preference for Contraceptive Options as Proxy for HIV Prevention Methods Nur-Isterate, Nuvaring, Triphasil - HIV | Not applicable | Unknown | Desmond Tutu HIV Centre | 131 | 2015-07-01 | 2019-02-11 |
| Examining HIV Treatment Adherence During Early Disease Medication Adherence, HIV | Completed | Massachusetts General Hospital | 904 | 2015-02-01 | 2018-08-16 | |
| Preparing for Adolescent HIV Vaccine Trials in South Africa: HIV Infection, HIV Infections | Unknown | Desmond Tutu HIV Centre | 1400 | 2009-08-01 | 2009-08-17 |
Acquired Immunodeficiency Syndrome (2) · HIV Infections (2) · Medication Adherence (1) · Sexually Transmitted Diseases (1) · Tuberculosis (1)
dolutegravir (2) · Darunavir (1) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Ethinyl Estradiol-Norgestrel Combination (1) · Rifampin (1) · Ritonavir (1) · Tablets (1)
South Africa (8) · Uganda (2)
Linda-Gail Bekker, MBChB, PhD (2) · Andrew Medina-Marino, PhD (1) · Geri R Donenberg, PhD (1) · Helen McIlleron, PhD (1) · Jessica Haberer, MD (1) · Linda-Gail Bekker, MBChB PhD (1) · Linda-Gail Bekker, MBChB, DTMH, DCH, FCP, PhD (1) · Saye Khoo (1)
PMID 32411946, PMID 32989170, PMID 33034421, PMID 33149114, PMID 33247553, PMID 34311754, PMID 35348351, PMID 35583344, PMID 35653046, PMID 36962830, PMID 37758649, PMID 37919697, PMID 38081955, PMID 40240718
R01MH114648 (1)