4 completed, 3 terminated. 6 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 6 | Completed 4, Terminated 2 |
| Phase 3 | 2 | Terminated 2 |
| Phase 1 | 1 | Completed 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hidradenitis Suppurativa Study of Izokibep Placebo, Izokibep - Hidradenitis Suppurativa | Phase 3 | Terminated | ACELYRIN Inc. | 258 | 2023-06-22 | 2025-10-15 |
| Efficacy and Safety of Lonigutamab in Subjects With Thyroid Eye Disease (TED) lonigutamab, Placebo - Thyroid Eye Disease | Phase 1 / Phase 2 | Completed | ACELYRIN Inc. | 31 | 2023-02-14 | 2025-07-01 |
| Psoriatic Arthritis Study of Izokibep Izokibep, Placebo to izokibep - Psoriatic Arthritis | Phase 2 / Phase 3 | Terminated | ACELYRIN Inc. | 351 | 2022-11-21 | 2025-05-23 |
| Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis Izokibep, Placebo - Uveitis | Phase 2 | Terminated | ACELYRIN Inc. | 96 | 2022-08-23 | 2025-02-21 |
| Hidradenitis Suppurativa Phase 2b Study of Izokibep Izokibep, Placebo to izokibep - Hidradenitis Suppurativa | Phase 2 | Completed | ACELYRIN Inc. | 205 | 2022-05-05 | 2025-06-03 |
| A Trial of the Efficacy and Safety of Izokibep in the Treatment of Non-anterior Uveitis Izokibep, Prednisone/Prednisolone - Uveitis | Phase 2 | Completed | ACELYRIN Inc. | 7 | 2022-01-06 | 2024-02-12 |
| A Study to Investigate Efficacy, Tolerability and Safety of ABY-035 in Patients With Active Psoriatic Arthritis ABY-035, Placebo - Psoriatic Arthritis | Phase 2 | Completed | ACELYRIN Inc. | 129 | 2020-08-04 | 2024-02-09 |
Arthritis, Psoriatic (2) · Hidradenitis Suppurativa (2) · Uveitis (2) · Arthritis (1) · Graves Ophthalmopathy (1) · Psoriasis (1) · Uveitis, Intermediate (1) · Uveitis, Posterior (1)
Prednisolone (1) · Prednisone (1)
United States (6) · Germany (5) · Spain (5) · Hungary (4) · Poland (4) · Canada (3) · Czechia (3) · Austria (2) · France (2) · Australia (1) · Belgium (1) · Bulgaria (1) · Italy (1) · Japan (1)
Donald Betah, MD (2) · Donald Betah (1) · Myreen Tomas, MD (1) · Shepard Mpofu, MD, Clinical Development (1) · Shephard Mpofu (1)