Maternal Pre‐pregnancy Overweight or Obesity and Risk of Birth Defects in Offspring: Population‐based Cohort Study

Weiying Liu; Luzhong Ren; Fang Fang; Ruoqing Chen;

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ABSTRACT

Maternal obesity, a health condition increasingly prevalent worldwide, has been suggested to be associated with a higher risk of birth defects in offspring, whereas evidence from population‐based data from China was largely lacking. Additionally, the role of gestational diabetes in the association between maternal obesity and birth defects remains unclear. We aimed to investigate the association of maternal pre‐pregnancy overweight or obesity with any and different types of birth defects in offspring and the interaction between pre‐pregnancy overweight or obesity and gestational diabetes.

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