Observed Prevalence of Congenital Situs Inversus in The United States Before and During The SARS‐CoV‐2 Pandemic, 2017–2022

Birth Defects Research  ·  2024

Janet D Cragan; S. Cho; Nina E Forestieri; Michele Hort; Eirini Nestoridi; C. A. Moore; Erin B Stallings; Elizabeth B Gray; J. Reefhuis;

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ABSTRACT

Reports from China describe an increase in the frequency of fetal situs inversus in 2023 after the country's “zero‐Covid” policy was lifted, suggesting an association with maternal SARS‐CoV‐2 infection. However, a report of birth defects surveillance data from Scandinavia observed no sustained increase during the SARS‐CoV‐2 pandemic (2020–2022 vs. 2018–2019). We examined birth defects surveillance data to assess any increase in situs inversus in the U.S. during the SARS‐CoV‐2 pandemic.

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