11 completed, 2 active not recruiting. 9 Phase 1, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 9 | Completed 9 |
| Phase 3 | 3 | Active not recruiting 2, Completed 1 |
| Phase 2 | 1 | Completed 1 |
Follow ZSP1273: new trials by email Literature Review of ZSP1273 trials Research Report on ZSP1273
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of ZSP1273 in Children 2-11 Years Old With Influenza A ZSP1273, Oseltamivir - Influenza a | Phase 3 | Active not recruiting | Guangdong Raynovent Biotech Co., Ltd | 119 | 2025-11-22 | 2025-12-16 |
| Efficacy and Safety of ZSP1273 in Children 12-17 Years Old With Influenza A ZSP1273, Placebo - Influenza A | Phase 3 | Active not recruiting | Guangdong Raynovent Biotech Co., Ltd | 157 | 2025-11-08 | 2025-12-16 |
| Pharmacokinetics of ZSP1273 in Participants With Severe Kidney Disease ZSP1273 - Kidney Impairment | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 16 | 2024-01-15 | 2025-03-19 |
| Bioavailability Study in Healthy Participants, 200mg Tablets ZSP1273 Versus 200mg Granules ZSP1273 ZSP1273 tablet, zsp1273 granules - Bioequivalence | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 32 | 2023-11-23 | 2024-01-29 |
| Pharmacokinetics of ZSP1273 in Elder Participants ZSP1273 - Elder | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 32 | 2023-10-11 | 2023-12-05 |
| Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid Digoxin, Rosuvastatin, ZSP1273 - Drug Drug Interaction | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 49 | 2023-07-10 | 2024-01-29 |
| A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam ZSP1273 - Drug Drug Interaction, Warfarin | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 28 | 2023-06-25 | 2023-12-06 |
| Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment ZSP1273 - Hepatic Impairment, Pharmacokinetics | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 24 | 2023-06-15 | 2023-12-01 |
| Mass Balance Study of [14C]ZSP1273 in Healthy Adult Male Subjects in China [14C] ZSP1273 - Pharmacokinetics | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 6 | 2023-03-25 | 2025-03-21 |
| A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral) - Influenza A | Phase 3 | Completed | Guangdong Raynovent Biotech Co., Ltd | 750 | 2020-12-28 | 2023-06-27 |
| Study to Investigate the Potential Drug-Drug Interaction Between ZSP1273 and Oseltamivir ZSP1273, Oseltamivir - Drug-drug Interaction | Phase 1 | Completed | Guangdong Raynovent Biotech Co., Ltd | 36 | 2020-11-19 | 2021-11-04 |
| Study of ZSP1273 in Patients With Acute Uncomplicated Influenza A ZSP1273 200 mg, Placebo, ZSP1273-400 mg - Influenza A | Phase 2 | Completed | Guangdong Raynovent Biotech Co., Ltd | 172 | 2019-12-07 | 2020-06-04 |
| The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers. ZSP1273 100 mg, Placebo 100 mg, ZSP1273 200 mg - Influenza | Phase 1 | Completed | Guangdong Zhongsheng Pharmaceutical Co., Ltd. | 103 | 2018-09-20 | 2019-08-14 |
Influenza, Human (1) · Renal Insufficiency (1)
Guangdong Raynovent Biotech Co., Ltd (12) · Guangdong Zhongsheng Pharmaceutical Co., Ltd. (1)
China (13)
Shucheng Hua, MD (1) · Yanhua Ding, MD (1)
PMID 34654349, PMID 38330975, PMID 39287964, PMID 39992105, PMID 40489986, PMID 40757817