4 completed. 4 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
| Phase 2 | 1 | Completed 1 |
Follow VRC01LS: new trials by email Literature Review of VRC01LS trials Research Report on VRC01LS
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Dual bNAb Treatment in Children ART, VRC01LS, 10-1074 - HIV Infection | Phase 1 / Phase 2 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 30 | 2019-06-17 | 2026-05-04 |
| Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic Adults VRC-HIVMAB080-00-AB, VRC-HIVMAB075-00-AB - HIV-1 | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 16 | 2017-04-24 | 2025-01-30 |
| Evaluating the Safety, Pharmacokinetics, and Anti-Viral Activity of VRC01 and VRC01LS in the Serum and Mucosa of Healthy, HIV-Uninfected Adults VRC01, VRC01LS - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 80 | 2017-03-01 | 2024-03-20 |
| Evaluating the Safety and Pharmacokinetics of VRC01, VRC01LS, and VRC07-523LS, Potent Anti-HIV Neutralizing Monoclonal Antibodies, in HIV-1-Exposed Infants VRC01, VRC01LS, VRC07-523LS - HIV Infections | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 83 | 2015-06-30 | 2023-02-08 |
HIV Infections (3)
National Institute of Allergy and Infectious Diseases (NIAID) (4)
United States (3) · Puerto Rico (2) · South Africa (2) · Botswana (1) · Zimbabwe (1)
Coleen Cunningham, MD (1) · Daniel Kuritzkes, MD (1) · Julie McElrath (1) · Linda-Gail Bekker (1) · Martin R Gaudinski, M.D. (1) · Mathias Lichterfeld, MD, PhD (1) · Roger Shapiro, MD, MPH (1)
PMID 31681963, PMID 34009371, PMID 36094485, PMID 37406137, PMID 38536810, PMID 39609400, PMID 39989458, PMID 40136003, PMID 41078080, PMID 41697750